Recombinant Human IL31 Protein, His-tagged
Cat.No. : | IL31-2311H |
Product Overview : | Recombinant Human IL31 Protein (Ser24-Thr164) with a N-His tag was expressed in E. coli. |
- Specification
- Gene Information
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Description : | IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 19.2 kDa Accurate Molecular Mass: 19 kDa |
Protein length : | Ser24-Thr164 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 97% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | IL31 interleukin 31 [ Homo sapiens (human) ] |
Official Symbol : | IL31 |
Synonyms : | IL31; interleukin 31; interleukin-31; IL 31; IL-31; |
Gene ID : | 386653 |
mRNA Refseq : | NM_001014336 |
Protein Refseq : | NP_001014358 |
MIM : | 609509 |
UniProt ID : | Q6EBC2 |
Products Types
◆ Lysates | ||
IL31-5227HCL | Recombinant Human IL31 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (6)
Ask a questionThe IL31 may have specificity for specific diseases, with relatively few side effects being a big advantage.
IL31 activates downstream signaling pathways by binding to receptors and participates in inflammatory response and immune regulation.
It has a wide range of applications in immune inflammation, dermatology and other research fields.
Clinical studies of IL31 are ongoing, but there is no clear therapeutic effect and effectiveness assessment at this time.
IL31 research still faces many challenges, including side effect evaluation, efficacy verification and other issues, and further efforts are needed.
Optimal dose may be related to individual differences, disease type and other factors, and the appropriate dose should be determined under the guidance of a doctor when using IL31.
Customer Reviews (3)
Write a reviewIL31 product has strict quality control and complies with relevant industry standards.
It performs well in biological activity tests.
This protein has high yield and good economic benefits.
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