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KRAS

  • Official Full Name

    v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

  • Overview

    GTPase KRas also known as V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog and KRAS, is a protein that in humans is encoded by the KRAS gene. Like other members of the Ras family, the KRAS protein is a GTPase and is an early player in many signal transduction pathways. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus. The protein product of the normal KRAS gene performs an essential function in normal tissue signaling, and the mutation of a KRAS gene is an essential step in the development of many cancers.
  • Synonyms

    KRAS; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; KRAS2, v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog; GTPase KRas; KRAS1; K-Ras 2; c-Ki-ras; oncogene KRAS2; K-ras p21 protein; c-Kirsten-ras protein; PR310 c-K-ras oncogene; transformi;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 insect cells
  • Wheat Germ
  • Avi
  • biotinylated
  • C
  • His
  • Myc
  • DDK
  • DYKDDDDK
  • Flag
  • GST
  • His (Fc)
  • His(N
  • ter)
  • MYC
  • Myc|DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KRAS-547H Recombinant Human Kirsten rat sarcoma viral oncogene homolog, His-tagged E.coli His
Human KRAS-29908TH Recombinant Human KRAS E.coli N/A
Human KRAS-455H Recombinant Human KRAS Protein, His-tagged E.coli His
Human KRAS-2569H Recombinant Human KRAS, His-tagged E.coli His
Human KRAS-163H Recombinant Human KRAS protein, MYC/DDK-tagged HEK293 Myc/DDK
Human KRAS-325H Recombinant Human KRAS protein(Thr2-Cys185(61Q)), His-tagged E.coli N-His Thr2-Cys185(61Q)
Human KRAS-1246H Recombinant Human V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog E.coli N/A
Human KRAS-456H Recombinant Human KRAS Protein, His-tagged E.coli His
Human KRAS-4885HCL Recombinant Human KRAS 293 Cell Lysate HEK293 N/A
Human KRAS-01H Recombinant Human KRAS G12D mutant Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-358H Recombinant Human KRAS Protein, His-tagged E.coli His
Human KRAS-0945H Recombinant Human KRAS (G12V) Protein (2-186), N-His tagged E.coli N-His 2-186
Human KRAS-4376H Recombinant Human KRAS Protein (Met1-Arg149), N-His tagged E.coli N-His Met1-Arg149
Human KRAS-19H Recombinant Human KRAS protein, His-tagged Insect Cell His Met 1 - Lys 169
Human KRAS-4374H Recombinant Human KRAS Protein (Met1-Val186), C-His tagged Mammalian cells C-His Met1-Val186
Human KRAS-0947H Recombinant Human KRAS Protein (T2-K169, G12D), Tag Free E.coli No tag T2-K169, G12D
Human KRAS-4377H Recombinant Human KRAS Protein (Met1-Met188), N-GST tagged E.coli N-GST Met1-Met188
Human KRAS-456HAF555 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 555 conjugated E.coli His 202
Human KRAS-458H Recombinant Human KRAS protein(G12D, Q61H), His-tagged E.coli His Thr2-Cys185
Human KRAS-0952H Recombinant Human KRAS Protein (T2-K169, G12R), Tag Free E.coli No tag T2-K169, G12R
Human KRAS-4378H Recombinant Human KRAS Protein (Thr2-Cys184), N-His tagged E.coli N-His Thr2-Cys184
Human KRAS-456HAF647 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 647 conjugated E.coli His 202
Human KRAS-031H Recombinant Human KRAS Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human KRAS-0954H Recombinant Human KRAS Protein (T2-K169, G12V), GST tagged E.coli GST T2-K169, G12V
Human KRAS-3489H Active Recombinant Human KRAS Protein, His-tagged E.coli His
Human KRAS-100H Recombinant Human KRAS G12D, Isoform A, GppNHp-loaded, N-His-tagged E.coli N-His 2-186
Human KRAS-085H Recombinant Human KRAS Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-0961H Recombinant Human KRAS Protein (T2-K169, G12R), GST tagged E.coli GST T2-K169, G12R
Human KRAS-083H Recombinant Human KRAS G12A mutant Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-101H Recombinant Human KRAS G12D, Isoform A, GDP-loaded, N-His-tagged E.coli N-His 2-186
Human KRAS-078H Recombinant Human KRAS G13D mutant Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-0963H Recombinant Human KRAS Protein (M1-M188, Q61R), Biotinylated tagged E.coli biotinylated M1-M188, Q61R
Human KRAS-082H Recombinant Human KRAS G12C mutant Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-0956H Recombinant Human KRAS Protein (T2-K169, G12D), GST tagged E.coli GST T2-K169, G12D
Human KRAS-454H Recombinant Human KRAS(Thr2-Cys185(Gly12Val)) Protein, N-6*His-tagged E.coli His
Human KRAS-1264H-B Recombinant Human KRAS Protein Pre-coupled Magnetic Beads HEK293
Human KRAS-081H Recombinant Human KRAS G12D mutant Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-0957H Recombinant Human KRAS Protein (T2-K169, G13D), GST tagged E.coli GST T2-K169, G13D
Human KRAS-459H Recombinant Human KRAS(Thr2-Cys185(Gly12 Ser)) Protein, N-6*His-tagged E.coli His
Human KRAS-1232H Recombinant Human KRAS protein, His-tagged E.coli His Thr2-Cys185(G12C)
Human KRAS-080H Recombinant Human KRAS G12S mutant Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-0958H Recombinant Human KRAS Protein (T2-K169, G12C), GST tagged E.coli GST T2-K169, G12C
Human KRAS-450H Recombinant Human KRAS(Met1-Lys169(Gly12Cys)) Protein, N-6*His-tagged E.coli His
Human KRAS-33H Recombinant Human KRAS Protein (1-186aa), N-His tagged E.coli N-His 1-186aa
Human KRAS-451H Recombinant Human KRAS(Met1-Lys169) Protein, N-6*His-tagged E.coli His
Human KRAS-0959H Recombinant Human KRAS Protein (T2-K169), GST tagged E.coli GST T2-K169
Human KRAS-10H Recombinant Human KRAS (G12C) Mutant Protein, His-tagged E.coli His
Human KRAS-4373H Recombinant Human KRAS Protein (Met1-Met188), N-His tagged E.coli N-His Met1-Met188
Human KRAS-09H Recombinant Human KRAS G12C Protein, AviTag™, Biotinylated E.coli Avi 1-185
Human KRAS-0960H Recombinant Human KRAS Protein (T2-K169, G12A), GST tagged E.coli GST T2-K169, G12A
Human KRAS-04H Recombinant Human KRAS Protein, Myc/DDK-tagged HEK293 Myc/DDK
Human KRAS-3259H Recombinant Human KRAS protein(Thr2-Cys185(G12D)), His-tagged E.coli N-His Thr2-Cys185(G12D)
Human KRAS-11H Recombinant Human KRAS G12V Protein, AviTag™, Biotinylated E.coli Avi 1-185
Human KRAS-66H Recombinant Human KRAS Protein (G12C), GST-Tagged E.coli GST
Human KRAS-3965HAF488 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 488 conjugated E.coli His 195
Human KRAS-4888H Recombinant Human KRAS Protein, GST-tagged Wheat Germ GST
Human KRAS-12H Recombinant Human KRAS G13D Protein, AviTag™, Biotinylated E.coli Avi 1-185
Human KRAS-67H Recombinant Human KRAS Protein (G12R), GST-Tagged, GppNHp Loaded E.coli GST
Human KRAS-456HAF488 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 488 conjugated E.coli His 202
Human KRAS-75H Recombinant Human KRAS Protein, GST-tagged E.coli GST 188
Human KRAS-05H Recombinant Human KRAS Protein, AviTag™ E.coli Avi 1-185
Human KRAS-68H Recombinant Human KRAS Protein (G12V), GST-Tagged, GppNHp Loaded E.coli GST
Human KRAS-455HAF555 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 555 conjugated E.coli His 202
Human KRAS-457H Recombinant Human KRAS protein(G12C, Q61H), His-tagged E.coli His Thr2-Cys185
Human KRAS-16H Recombinant Human KRAS G12V Protein, Avi Tag E.coli Avi 1-185
Human KRAS-2227H Recombinant Human KRAS protein, His&Avi-tagged, Biotinylated E.coli His&Avi Thr2-Cys185(G12D)
Human KRAS-3965HAF647 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 647 conjugated E.coli His 195
Human KRAS-084H Recombinant Human KRAS Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-17H Recombinant Human KRAS G13D Protein, Avi Tag E.coli Avi 1-185
Human KRAS-079H Recombinant Human KRAS G12V mutant Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human KRAS-3965HF Recombinant Human KRAS Protein, His-tagged, FITC conjugated E.coli His 195
Human KRAS-02H Recombinant Human KRAS (G12D) Protein, His-tagged E.coli His
Human KRAS-0948H Recombinant Human KRAS Protein (T2-K169, G13D), Tag Free E.coli No tag T2-K169, G13D
Human KRAS-452H Recombinant Human KRAS(Met1-Lys169) Protein, N-6*His-tagged E.coli His
Human KRAS-456HF Recombinant Human KRAS Protein, His-tagged, FITC conjugated E.coli His 202
Human KRAS-03H Recombinant Human KRAS Protein, DYKDDDDK-tagged Human Cell DYKDDDDK
Human KRAS-0949H Recombinant Human KRAS Protein (T2-K169, G12C), Tag Free E.coli No tag T2-K169, G12C
Human KRAS-455HAF488 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 488 conjugated E.coli His 202
Human KRAS-5845HF Recombinant Full Length Human KRAS Protein, GST-tagged In Vitro Cell Free System GST 188 amino acids
Human KRAS-3965HAF555 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 555 conjugated E.coli His 195
Human KRAS-0950H Recombinant Human KRAS Protein (T2-K169), Tag Free E.coli No tag T2-K169
Human KRAS-455HAF647 Recombinant Human KRAS Protein, His-tagged, Alexa Fluor 647 conjugated E.coli His 202
Human KRAS-06H Recombinant Human KRAS Protein, AviTag™, Biotinylated E.coli Avi 1-185
Human KRAS-455HF Recombinant Human KRAS Protein, His-tagged, FITC conjugated E.coli His 202
Human KRAS-0951H Recombinant Human KRAS Protein (T2-K169, G12A), Tag Free E.coli No tag T2-K169, G12A
Human KRAS-224H Recombinant Human KRAS Protein, His-tagged(N-ter) E.coli His(N-ter) Thr2-Cys186
Human KRAS-08H Recombinant Human KRAS Q61H Protein, AviTag™, Biotinylated E.coli Avi 1-185
Human KRAS-07H Recombinant Human KRAS Q61H Protein, AviTag™ E.coli Avi 1-185
Human KRAS-13H Recombinant Human KRAS (G12D) Protein (1-186), N-His-tagged E.coli N-His 1-186
Human KRAS-14H Recombinant Human KRAS G12D Protein, Avi Tag E.coli Avi 1-185
Human KRAS-15H Recombinant Human KRAS G12D protein, Avi Tag, Biotinylated E.coli Avi 1-185
Human KRAS-103H Recombinant Human KRAS, Isoform B, GDP-Loaded, N-His-tagged Sf9 insect cells N-His 2-186
Human KRAS-102H Recombinant Human KRAS, Isoform B, BODIPY-GDP Loaded, N-His-tagged Sf9 insect cells N-His 2-186
Human KRAS-40HFL Recombinant Full Length Human KRAS Protein, C-Flag-tagged Mammalian cells Flag
Human KRAS-1264H Recombinant Human KRAS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human KRAS-0944H Recombinant Human KRAS Protein (M1-K169), Tag Free E.coli No tag M1-K169
Human KRAS-0946H Recombinant Human KRAS Protein (T2-K169, G12S), Tag Free E.coli No tag T2-K169, G12S
Human KRAS-0953H Recombinant Human KRAS Protein (M1-K169), His tagged E.coli His M1-K169
Human KRAS-0955H Recombinant Human KRAS Protein (T2-K169, G12S), GST tagged E.coli GST T2-K169, G12S
Human KRAS-0962H Recombinant Human KRAS Protein (M1-M188, Q61K), Biotinylated tagged E.coli biotinylated M1-M188, Q61K
Mouse KRAS-8806M Recombinant Mouse KRAS Protein Mammalian Cell His
Mouse KRAS-4903M Recombinant Mouse KRAS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse KRAS-4903M-B Recombinant Mouse KRAS Protein Pre-coupled Magnetic Beads HEK293
Mouse Kras-1283M Recombinant Mouse Kras Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rhesus Macaque KRAS-2443R Recombinant Rhesus monkey KRAS Protein, His-tagged Mammalian Cell His
Rhesus Macaque KRAS-2264R Recombinant Rhesus Macaque KRAS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque KRAS-2264R-B Recombinant Rhesus Macaque KRAS Protein Pre-coupled Magnetic Beads HEK293
Zebrafish KRAS-1084Z Recombinant Zebrafish KRAS Mammalian Cell His
Chicken KRAS-4583C Recombinant Chicken KRAS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource
  • KRAS Related Signal Pathway

KRAS involved in several pathways and played different roles in them. We selected most pathways KRAS participated on our site, such as MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with KRAS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayHSPA1B;FGFR2;MAP2K5;PPM1NA;CACNA1D;MAX;GADD45AA;STK3;GRB2A
ErbB signaling pathwayABL2;PTK2AB;GRB2B;ABL1;PAK6;AKT2L;MAPK8;GRB2;PAK2A
Ras signaling pathwayGNG5;SHC3;RALGDS;AKT1;ANGPT4;CSF1;IKBKB;ABL1;PAK7
Rap signaling pathwayHRAS;RAPGEF5;PIK3R5;FLT1;AKT2;PRKCZ;IGF1;GNAI2;PRKCI
Chemokine signaling pathwaySHC1;ADRBK2;CCL6;MAPK1;KRAS;CCR6;ADRBK1;Adcy4;PIK3CB
FoxO signaling pathwayAKT2L;INSRB;SGK3;MDM2;IL7R;SIRT1;PRKAG3B;PIK3CB;ATG12
Sphingolipid signaling pathwayPIK3CG;MAPK10;PIK3CD;PPP2R5A;RELA;MS4A2;PPP2R5E;PLD1;DEGS1
Phospholipase D signaling pathwayCYTH4;PTPN11;AVP;GRM5;PIK3CA;PIK3CB;GRM3;HRAS;F2R
PIK-Akt signaling pathwayOSMR;NGFR;HGF;IFNA2;IFNA12;FGF6;PPP2R2D;COL6A4;CCND3
Dorso-ventral axis formationGRB2;ETV7;NOTCH1B;PIWIL2;ETV6;PPP1R2P9;NOTCH4;PIWIL4;CPEB1B
Axon guidanceFGF18B;PPP3CC;RANBP9;EFNB3B;CDK5R1B;TRPC7;DUSP6;ARPC1A;SPNA2
VEGF signaling pathwayMAPK14B;SHC2;MAPK11;RAC2;CDC42L2;PTGS2A;HRASA;SPHK2;PPP3CB
Tight junctionGNAI2B;MYLPFB;CLDN1;CDC42;MYL7;MYL9B;INADL;CLDN15;OCLNB
Gap junctionPRKCA;PDGFAA;GNAIA;PLCB1;TUBA1B;PRKG1A;DRD2A;TUBA3E;PRKCB
Signaling pathways regulating pluripotency of stem cellsMAPK3;WNT5B;INHBB;MYF5;PIK3CB;SMAD3;GSK3B;NANOG;FZD5
Natural killer cell mediated cytotoxicityIFNA7;NFATC1;PPP3CB;PRF1;MAPK3;PIK3CD;IFNAR2;ARAF;CD244
T cell receptor signaling pathwayPIK3R1;Il2;MAP3K7;TNF;PPP3R2;IFNG;IL4;PPP3CC;NFKBIB
B cell receptor signaling pathwayINPP5D;LCP2A;CDK2;PLEKHA1;NFKBIE;PPP3CC;DOK1;ITPR2;KRAS
Fc epsilon RI signaling pathwayNRAS;RAC1;TNF;PIK3CG;MAP2K4;IL5;RAC3;LYN;PIK3R5
Long-term potentiationRPS6KA6;BRAF;HRAS;PPP3CA;MAPK1;CAMK2B;GRM1;CAMK2G;RPS6KA1
Neurotrophin signaling pathwayARHGDIA;CDC42;SHC4;CALM4;SH2B3;MAPK1;SH2B1;MAPK11;IRS1
Cholinergic synapsePIK3R5;GNG4;FOS;KCNQ5;PIK3R1;CAMK2B;PRKACA;ITPR1;Adcy4
Serotonergic synapseGNAO1;MAP2K1;SLC6A4;HTR2B;PLCB1;HTR5A;PLCB2;PRKCA;ALOX12E
Long-term depressionGNAQ;PLCB2;ARAF;ITPR3;BRAF;GUCY1A3;GNAS;IGF1;GNAI1
Regulation of actin cytoskeletonCFL2;ITGA10;MYL5;BRK1;ITGB2;PIP5KL1;MYLPFA;RHOAC;PPP1R12B
Insulin signaling pathwayCALM1A;TSC1B;PDPK1;G6PCA.1;PPP1CB;FBP1A;PHKA2;PIK3R5;PIK3R3A
GnRH signaling pathwayPRKCB;ADCY1A;CALM;CACNA1DA;CALM1A;MAP2K4B;HRASB;GNRHR4;MAPK11
Progesterone-mediated oocyte maturationARAF;PIK3CA;PGR;PRKACA;HSP90AA1.1;CDC25B;PIK3CD;RPS6KAL;GNAIA
Estrogen signaling pathwayCREB3L1;HSP90B1;KCNJ3;KCNJ5;HSPA2;PLCB1;FKBP5;HSPA1L;ESR1
MelanogenesisKRAS;EDNRB2;WNT7AA;WNT6;GNAI3;TCF7;TCF7L1A;CALM1;PLCB2
Prolactin signaling pathwayNEK3;GSK3B;MAPK13;SOCS6;FOS;IRF1;INS;SOCS5;ELF5
Thyroid hormone signaling pathwayATP1A4;HDAC2;PLCB3;FOXO1;WNT4;ITGB3;HDAC1;AKT2;RHEB
Oxytocin signaling pathwayPLCB1;ITPR3;PIK3CA;CACNB1;MYLK4;TRPM2;CAMK2A;PLCB4;PPP3CA
Aldosterone-regulated sodium reabsorptionALPHA-ENAC;PIK3CD;ATP1B3;PIK3CG;IRS1;PRKCG;INSR;KCNJ1;PRKCB
AlcoholismHIST2H3C2;HIST1H2BK;HIST1H4C;GNG10;GRIN1;SLC6A3;HIST1H2AC;HIST1H2BP;HIST2H2BB
Hepatitis CIFNA16;SOCS3;TRADD;PPP2R1B;IFNA2;RELA;TRAF6;OAS3;GRB2
Hepatitis BIFNA2;YWHAB;HBXIP;PRKCA;STAT5B;PRKCG;MAVS;PIK3CA;IFNA21
HTLV-I infectionTBP;ITGB2;XPO1;HLA-F;POLB;AKT1;HRAS;FZD5;PPP3R2
Pathways in cancerCSF1R;NOS2;GNG3;MAPK3;LAMC2;LAMB1;BCL2L1;BDKRB1;PIK3CA
Viral carcinogenesisHPN;MDM2;MAPKAPK2;GTF2E2;GSN;HLA-F;PMAIP1;HIST1H4H;NRAS
Proteoglycans in cancerTGFB2;ESR1;PTCH1;SMO;WNT11;MAPK3;Fasl;HGF;FASLG
MicroRNAs in cancerPDGFRB;HOXD10;SLC7A1;TRP63;PTGS2;PIM1;ERBB3;PDGFA;IKBKB
Colorectal cancerMSH2;SMAD2;MAPK10;AXIN2;TGFB3;PIK3CG;MSH3;RAC3;Casp3
Renal cell carcinomaBRAF;HGF;ARAF;ARNT2;EPAS1;GRB2;SOS1;EGLN2;AHA-1
Pancreatic cancerTGFB1;PIK3CG;TRP53;BRAF;PIK3CA;RAC2;RALBP1;KRAS;SMAD2
Endometrial cancerPDPK1;ELK1;PIK3CB;PIK3R3;SOS1;AKT2;PTEN;AXIN1;MLH1
GliomaSHC4;GRB2;KRAS;PIK3R5;MDM2;PIK3CD;PIK3R3;IGF1R;PRKCB
Prostate cancerAKT2;ARID1A;AKT1;CREB5;SMARCD1;HSP90B1;PDGFRA;FGFR1;PDGFB
Thyroid cancerKRAS;TCF7L2;NRAS;NTRK1;RXRB;TPR;MAP2K2;RXRA;NCOA4
MelanomaPIK3CA;PDGFA;FGF20;CDH1;PIK3CB;AKT2;PTEN;FGF6;FGF7
Bladder cancerMAP2K1;SRC;MAP2K2;RPS6KA5;TRP53;RB1;TYMP;RAF1;CXCL8
Chronic myeloid leukemiaCDK6;MECOM;CBLC;ARAF;TGFBR1;IKBKB;TGFB2;SHC3;TGFBR2
Acute myeloid leukemiaSPI1;RARA;MAPK1;CCNA1;RUNX1T1;RPS6KB2;RAF1;RUNX1;LEF1
Non-small cell lung cancerPRKCB;BRAF;PIK3R1;AKT2;PIK3R3;ALK;PIK3CA;MAPK3;MAP2K2
Central carbon metabolism in cancerLDHA;FGFR2;HRAS;SLC2A1;PDHA1;TRP53;PDGFRA;RET;PFKL
Choline metabolism in cancerTSC2;NRAS;PIK3CB;PDGFA;PPAP2A;RAC1;WAS;MAP2K2;WASF1

KRAS has several biochemical functions, for example, GDP binding, GMP binding, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KRAS itself. We selected most functions KRAS had, and list some proteins which have the same functions with KRAS. You can find most of the proteins on our site.

Function Related Protein
GDP bindingRRAS;PIGC;RAB17;ARL8B;RAB8B;RAB31;RAB8A;RAB22A;PRPS1
GMP bindingKRAS;RAB26
GTP bindingAK4;RAB30;MRAS;SEPT5A;GNAZ;TUBA7L;TUBA4L;TUBA8;RAB3DB
LRR domain bindingKRAS;ROBO1;POLR2J;ZXDC;STK11;LRRFIP2
protein bindingHPCAL4;CNNM3;C22orf23;VAMP1;PTPN1;DGKQ;POP5;PDLIM5;MC4R
protein complex bindingTXN2;KRAS;ATF1;SREBF1;CPD;BAG3;PPP4C;HTR2A;WASF1

KRAS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRAS here. Most of them are supplied by our site. Hope this information will be useful for your research of KRAS.

ARAF; RASSF2; gtp; q46342_closo; Pik3ca; Rassf5; PIK3R2; RGL2; DEAF1; FRAT2; ZNF189; TNFSF13; DIRAS3; MOCS2; MT-CYB

Research Area

Related articles

Bettington, ML; Walker, NI; et al. A clinicopathological and molecular analysis of 200 traditional serrated adenomas. MODERN PATHOLOGY 28:414-427(2015).
Puzanov, I; Lindsay, CR; et al. A Phase I Study of Continuous Oral Dosing of OSI-906, a Dual Inhibitor of Insulin-Like Growth Factor-1 and Insulin Receptors, in Patients with Advanced Solid Tumors. CLINICAL CANCER RESEARCH 21:701-711(2015).
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