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Recombinant Human KRAS Protein, His-tagged

Cat.No. : KRAS-358H
Product Overview : Recombinant Human KRAS Protein is produced by E. coli expression system. This protein is fused with a His tag at the N-terminal.
  • Specification
  • Gene Information
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Description : The RAS gene superfamily encodes a group of closely related 21,000 dalton (p21) proteins with special affinity for guanine nucleotides (GTP). RAS and several other cellular proteins with similar biochemical properties are collectively known as G-proteins and they play key roles in a wide variety of cellular activities, including cell growth, differentiation, secretion, and protein trafficking. There are three forms of RAS gene in cells termed H-RAS, N-RAS, and K-RAS. RAS proteins play a direct causal role in human cancer and in other diseases. Mutant H-RAS, N-RAS, and K-RAS occur in varying frequencies in different tumor types. Other members of the RAS superfamily may also contribute to cancer.
Source : E. coli
Species : Human
Tag : His
Form : Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol,
Molecular Mass : 23 kDa
Purity : >85% by densitometry.
Applications : Enzyme Assay, Western Blot.
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog [ Homo sapiens ]
Official Symbol : KRAS
Synonyms : KRAS; GTPase KRas; KRAS1; K-Ras 2; c-Ki-ras; oncogene KRAS2; NS; NS3; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B;
Gene ID : 3845
mRNA Refseq : NM_004985
Protein Refseq : NP_004976
MIM : 190070
UniProt ID : P01116

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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