Recombinant Human V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog
Cat.No. : | KRAS-1246H |
Product Overview : | Recombinant humanKRAS containing 188 amino acids. |
- Specification
- Gene Information
- Related Products
Cat. No. : | KRAS-1246H |
Description : | KRAS proteins aremembers of the superfamily of small GTP-binding proteins that function asmolecular switches controlling a variety of signaling and transport pathways.KRAS, one of three classic human Ras genes, is spliced to two differentisoforms, K-RAS4A and K-RAS4B. K-RAS4B is the predominant product of thealternative splicing pathway and the KRAS protein encoded by the commonlymutated Ras gene in human cancer. Protein preparation is 100% GDP-loaded,measured by HPLC. |
Source : | E. coli |
Species : | Human |
Form : | Liquid in 64 mMTris-HCl, pH 7.2 + 10 mM MgCl2 + 5 mM DTE |
MolecularWeight : | 21.4 kDa |
Purity : | > 95% asdetermined by SDS-PAGE analysis |
Storage : | Stable for 1 yearin working aliquots at -80°C. Avoid repeated freeze-thaw cycles. |
OfficialSymbol : | KRAS |
Gene Name : | KRAS v-Ki-ras2 Kirsten ratsarcoma viral oncogene homolog [ Homo sapiens ] |
Synonyms : | KRAS; v-Ki-ras2Kirsten rat sarcoma viral oncogene homolog; NS; NS3; KRAS1; KRAS2; RASK2;KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; GTPase KRas; K-Ras 2;c-Ki-ras; oncogene KRAS2; K-ras p21 protein; OTTHUMP00000245391;OTTHUMP00000245393; c-Kirsten-ras protein; PR310 c-K-ras oncogene;transforming protein p21; cellular c-Ki-ras2 proto-oncogene; v-Ki-ras2Kirsten rat sarcoma 2 viral oncogene homolog; Kirsten rat sarcoma-2 viral(v-Ki-ras2) oncogene homolog |
Gene ID : | 3845 |
mRNA Refseq : | NM_004985 |
Protein Refseq : | NP_004976 |
MIM : | 190070 |
UniProt ID : | P01116 |
Chromosome Location : | 12p12.1 |
Pathway : | ARMS-mediatedactivation; B cell receptor signaling pathway; Cell surface interactions atthe vascular wall; Developmental Biology; EGFR1 Signaling Pathway; Fc epsilonRI signaling pathway; G Protein Signaling Pathways; HTLV-I infection; IL-2Signaling Pathway;; MAPK signaling pathway; Natural killer cell mediatedcytotoxicity; Pancreatic cancer; RAF phosphorylates MEK; SOS-mediatedsignalling; T cell receptor signaling pathway |
Function : | GDP binding; GMPbinding; GTP binding; GTPase activity; LRR domain binding; Ralguanyl-nucleotide exchange factor activity; nucleotide binding; proteinbinding |
Products Types
◆ Recombinant Protein | ||
KRAS-0955H | Recombinant Human KRAS Protein (T2-K169, G12S), GST tagged | +Inquiry |
KRAS-3259H | Recombinant Human KRAS protein(Thr2-Cys185(G12D)), His-tagged | +Inquiry |
KRAS-07H | Recombinant Human KRAS Q61H Protein, AviTag™ | +Inquiry |
KRAS-3489H | Active Recombinant Human KRAS Protein, His-tagged | +Inquiry |
KRAS-0951H | Recombinant Human KRAS Protein (T2-K169, G12A), Tag Free | +Inquiry |
◆ Lysates | ||
KRAS-4885HCL | Recombinant Human KRAS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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