Recombinant Human KRAS (G12D) Protein (1-186), N-His-tagged
Cat.No. : | KRAS-13H |
Product Overview : | Recombinant human KRAS (G12D, Isoform B) (1-186) was expressed in E. coli cells using an N-terminal His tag. KRASB (G12D) is constitutively active. |
- Specification
- Gene Information
- Related Products
Description : | This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Molecular Mass : | ~21 kDa |
Protein Length : | 1-186 |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Storage Buffer : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.25mM DTT, 25% glycerol. |
Gene Name : | KRAS KRAS proto-oncogene, GTPase [ Homo sapiens (human) ] |
Official Symbol : | KRAS |
Synonyms : | KRAS; KRAS proto-oncogene, GTPase; NS; NS3; OES; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras 2; 'C-K-RAS; c-Ki-ras; c-Ki-ras2; GTPase KRas; K-ras p21 protein; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral proto-oncogene; PR310 c-K-ras oncogene; c-Kirsten-ras protein; cellular c-Ki-ras2 proto-oncogene; cellular transforming proto-oncogene; oncogene KRAS2; proto-oncogene GTPase; transforming protein p21; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; EC 3.6.5.2 |
Gene ID : | 3845 |
mRNA Refseq : | NM_004985 |
Protein Refseq : | NP_004976 |
MIM : | 190070 |
UniProt ID : | P01116 |
Products Types
◆ Recombinant Protein | ||
KRAS-66H | Recombinant Human KRAS Protein (G12C), GST-Tagged | +Inquiry |
KRAS-081H | Recombinant Human KRAS G12D mutant Protein, DYKDDDDK-tagged | +Inquiry |
KRAS-05H | Recombinant Human KRAS Protein, AviTag™ | +Inquiry |
KRAS-080H | Recombinant Human KRAS G12S mutant Protein, DYKDDDDK-tagged | +Inquiry |
KRAS-0946H | Recombinant Human KRAS Protein (T2-K169, G12S), Tag Free | +Inquiry |
◆ Lysates | ||
KRAS-4885HCL | Recombinant Human KRAS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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