Recombinant Human KRAS Protein (G12C), GST-Tagged
Cat.No. : | KRAS-66H |
Product Overview : | Recombinant Human KRAS Protein (G12C) with GST tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Molecular Mass : | 49.6 kDa |
Purity : | > 95% by SDS-PAGE |
Usage : | Used as a target for inhibition assays to develop treatment compounds for a variety of cancers. |
Storage : | Stable for 12 months at -80 centigrade, Avoid freeze/thaw cycles |
Storage Buffer : | PBS + 20% glycerol |
Gene Name : | KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog [ Homo sapiens (human) ] |
Official Symbol : | KRAS |
Synonyms : | KRAS; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog; KRAS2, v Ki ras2 Kirsten rat sarcoma 2 viral oncogene homolog; GTPase KRas; KRAS1; K-Ras 2; c-Ki-ras; oncogene KRAS2; K-ras p21 protein; c-Kirsten-ras protein; PR310 c-K-ras oncogene; transforming protein p21; cellular c-Ki-ras2 proto-oncogene; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; Kirsten rat sarcoma-2 viral (v-Ki-ras2) oncogene homolog; NS; NS3; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; |
Gene ID : | 3845 |
mRNA Refseq : | NM_004985 |
Protein Refseq : | NP_004976 |
MIM : | 190070 |
UniProt ID : | P01116 |
Products Types
◆ Recombinant Protein | ||
KRAS-102H | Recombinant Human KRAS, Isoform B, BODIPY-GDP Loaded, N-His-tagged | +Inquiry |
KRAS-0955H | Recombinant Human KRAS Protein (T2-K169, G12S), GST tagged | +Inquiry |
KRAS-103H | Recombinant Human KRAS, Isoform B, GDP-Loaded, N-His-tagged | +Inquiry |
KRAS-0958H | Recombinant Human KRAS Protein (T2-K169, G12C), GST tagged | +Inquiry |
KRAS-0944H | Recombinant Human KRAS Protein (M1-K169), Tag Free | +Inquiry |
◆ Lysates | ||
KRAS-4885HCL | Recombinant Human KRAS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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