Recombinant Full Length Human KRAS Protein, C-Flag-tagged
Cat.No. : | KRAS-40HFL |
Product Overview : | Recombinant Full Length Human KRAS Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 21.2 kDa |
AA Sequence : | MTEYKLVVVGAGGVGKSALTIQLIQ NHFVDEYDPTIEDSYRKQVVIDGET CLLDILDTAGQEEYSAMRDQ YMRTGEGFLCVFAINNTKSFEDIHH YREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIP FIETSAKTRQGVDDAFYTLVREIRK HKEKMSKDGKKKKKKSKTKCVIMTR TRPLEQKLISEEDLAANDILDYKDD DDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Protein Pathways : | Acute myeloid leukemia, Axon guidance, B cell receptor signaling pathway, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway, Thyroid cancer, Tight junction, VEGF signaling pathway |
Gene Name : | KRAS KRAS proto-oncogene, GTPase [ Homo sapiens (human) ] |
Official Symbol : | KRAS |
Synonyms : | NS; NS3; OES; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras 2; 'C-K-RAS; c-Ki-ras; c-Ki-ras2 |
Gene ID : | 3845 |
mRNA Refseq : | NM_004985.5 |
Protein Refseq : | NP_004976.2 |
MIM : | 190070 |
UniProt ID : | P01116 |
Products Types
◆ Recombinant Protein | ||
KRAS-04H | Recombinant Human KRAS Protein, Myc/DDK-tagged | +Inquiry |
KRAS-0959H | Recombinant Human KRAS Protein (T2-K169), GST tagged | +Inquiry |
Kras-1283M | Recombinant Mouse Kras Protein, MYC/DDK-tagged | +Inquiry |
KRAS-16H | Recombinant Human KRAS G12V Protein, Avi Tag | +Inquiry |
KRAS-358H | Recombinant Human KRAS Protein, His-tagged | +Inquiry |
◆ Lysates | ||
KRAS-4885HCL | Recombinant Human KRAS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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