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Official Full Name natural cytotoxicity triggering receptor 3
Background The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5 untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms NCR3; natural cytotoxicity triggering receptor 3; LY117, lymphocyte antigen 117; 1C7; CD337; NKp30; Natural killer cell p30 related protein; CD337 antigen; LY117; Lymphocyte antigen 117; NK-p30; OTTHUMP00000029162; OTTHUMP00000029163; OTTHUMP00000029164; OTTHUMP00000029165; activating NK-A1 receptor; activating natural killer receptor p30; natural killer cell p30-related protein; MALS
    • Species :
    • Cynomolgus
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Human Cells
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    • T7
    • His-Avi
    • human
    • IgG1
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human NCR3-151H Recombinant Human NCR3 Protein, His-tagged Human Cells His
    Human NCR3-100H Recombinant Human NCR3 protein, T7/His-tagged E.coli T7/His
    Human NCR3-2652HCL Recombinant Human NCR3 cell lysate Human Cell N/A
    Human NCR3-486H Recombinant Human NCR3 protein, His-tagged HEK293 His
    Human NCR3-5087H Recombinant Human NCR3, His-tagged E.coli His
    Human NCR3-582H Recombinant Human NCR3 protein, His-Avi-tagged HEK293 His-Avi
    Human NCR3-643H Recombinant Human NCR3, Fc-tagged, Biotinylated Human Cell Fc
    Human NCR3-785H Recombinant Human NCR3 protein, His-tagged HEK293 His
    Human NCR3-814H Recombinant Human NCR3 protein, Fc-tagged HEK293 human/IgG1/Fc
    Human NCR3-815H Recombinant Human NCR3, Fc-His tagged Human Cell Fc/His
    Human NCR3-816H Recombinant Human NCR3, His tagged Human Cell His
    Rat Ncr3-1158R Recombinant Rat Ncr3 Protein, His-tagged HEK293 His
    Rat Ncr3-1816R Recombinant Rat Ncr3 protein, His & T7-tagged E.coli His/T7
    Cynomolgus NCR3-498C Recombinant Cynomolgus NCR3 Protein, His-tagged HEK293 His
    Cynomolgus NCR3-499C Recombinant Cynomolgus NCR3 protein, His-tagged HEK293 His
    Rhesus Macaque NCR3-2961R Recombinant Rhesus monkey NCR3 Protein, His-tagged Mammalian Cell His

    ncr3 involved in several pathways and played different roles in them. We selected most pathways ncr3 participated on our site, such as Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with ncr3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Natural killer cell mediated cytotoxicity PIK3R5; IFNA16; IFNA5; GM-CSF; SAMD3; KIR2DS4; PPP3CC; CD247; KLRA8; HLA-B

    ncr3 has several biochemical functions, for example, cell adhesion molecule binding, protein homodimerization activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ncr3 itself. We selected most functions ncr3 had, and list some proteins which have the same functions with ncr3. You can find most of the proteins on our site.

    Function Related Protein
    cell adhesion molecule binding CD200; CAML; ITGB3; PVRL1A; PVRL2; CADM1; NLGN3; PTPRD; PTBP3; Fert2
    protein homodimerization activity USH1G; S100A16; NRBP1; IL6ST; GAMT; HMGCL; ANXA9; MTHFD1L; OLIG2; DMRTC2
    receptor activity VMN1R49; VMN1R46; MED16; PVRL3B; ITGB8; EPHB6; Pla2r1; PVRL1A; MCC; GRIK3
    receptor binding TNFSF13; SMARCD3; PVRL1; LPL; FGG; HSPA1A; ANGPTL1; CX3CL1; ENSA; INSL3

    ncr3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ncr3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ncr3.

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