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NCR3

  • Official Full Name

    natural cytotoxicity triggering receptor 3

  • Overview

    The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5 untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    NCR3; natural cytotoxicity triggering receptor 3; LY117, lymphocyte antigen 117; 1C7; CD337; NKp30; Natural killer cell p30 related protein; CD337 antigen; LY117; Lymphocyte antigen 117; NK-p30; OTTHUMP00000029162; OTTHUMP00000029163; OTTHUMP00000029164; OTTHUMP00000029165; activating NK-A1 receptor; activating natural killer receptor p30; natural killer cell p30-related protein; MALS;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Pan troglodytes (Chimpanzee)
  • Rat
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Human Cells
  • Mammalian Cell
  • Mammalian cells
  • C
  • Fc
  • hFc
  • His
  • Avi
  • Fc|His
  • His(C
  • ter)
  • His (Fc)
  • His|T7
  • human|IgG1|Fc
  • lFc
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NCR3-643H Active Recombinant Human NCR3, Fc-tagged, Biotinylated Human Cell Fc
Human NCR3-0563H Active Recombinant Human NCR3 protein, lFc-tagged HEK293 lFc Leu19-Gly135
Human NCR3-100H Recombinant Human NCR3 protein, T7/His-tagged E.coli T7/His
Human NCR3-486H Active Recombinant Human NCR3 protein, His-tagged HEK293 His Leu 19 - Gly 135
Human NCR3-5087H Recombinant Human NCR3, His-tagged E.coli His
Human NCR3-815H Recombinant Human NCR3, Fc-His tagged Human Cell Fc/His
Human NCR3-814H Recombinant Human NCR3 protein, Fc-tagged HEK293 human/IgG1/Fc 117
Human NCR3-816H Active Recombinant Human NCR3 protein, His-tagged HEK293 His Met1-Gly135
Human NCR3-2652HCL Recombinant Human NCR3 cell lysate Human Cell N/A
Human NCR3-785H Recombinant Human NCR3 protein, His-tagged HEK293 His Asp25-Ser262
Human NCR3-256H Recombinant Human NCR3 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Leu19-Thr138
Human NCR3-4177H Recombinant Human NCR3 Protein (Leu19-Gly135), C-Fc tagged Mammalian cells C-Fc Leu19-Gly135
Human NCR3-151H Recombinant Human NCR3 Protein, His-tagged Human Cells His
Human NCR3-044H Recombinant Human NCR3 Protein, C-His-tagged E.coli C-His
Human NCR3-4178H Recombinant Human NCR3 Protein (Leu19-Thr138), C-Fc tagged Mammalian cells C-Fc Leu19-Thr138
Human NCR3-4179H Recombinant Human NCR3 Protein (Leu19-Thr138), C-His tagged Mammalian cells C-His Leu19-Thr138
Human NCR3-398H Recombinant Human NCR3 Protein, His-tagged HEK293 His 201
Human NCR3-2693H Active Recombinant Human NCR3 protein, hFc&His-tagged HEK293 hFc&His Leu19-Thr138
Human NCR3-4180H Recombinant Human NCR3 Protein (Met1-Gly135), C-His tagged Mammalian cells C-His Met1-Gly135
Human NCR3-197H Recombinant Human NCR3 Protein, Leu19-Thr138, C-His-Avi tagged, Biotinylated HEK293 C-His-Avi Leu19-Thr138
Human NCR3-399H Recombinant Human NCR3 Protein, Fc-tagged HEK293 Fc 201
Human NCR3-664H Recombinant Human NCR3 Protein (Leu19-Glu135), C-hFc-tagged HEK293 C-hFc Leu19-Glu135
Human NCR3-0564H Active Recombinant Human NCR3 protein, Fc-tagged HEK293 Fc Leu19-Gly135
Human NCR3-582H Recombinant Human NCR3 protein, His-Avi-tagged HEK293 His-Avi Leu19-Thr138
Human NCR3-4176H Recombinant Human NCR3 Protein (Met1-Leu134), C-His tagged Mammalian cells C-His Met1-Leu134
Rat Ncr3-1816R Recombinant Rat Ncr3 protein, His & T7-tagged E.coli His/T7 Val21~Ser147 (Accession # Q8CFD9)
Rat Ncr3-1158R Active Recombinant Rat Ncr3 protein, His-tagged HEK293 His Met1-Ser147
Cynomolgus NCR3-498C Active Recombinant Cynomolgus NCR3 Protein, His-tagged HEK293 His Met1-Gly135
Cynomolgus NCR3-499C Recombinant Cynomolgus NCR3 protein, His-tagged HEK293 His Asp25-Asp259
Homo sapiens (Human) RFL8761HF Recombinant Full Length Human Natural Cytotoxicity Triggering Receptor 3(Ncr3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-201)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL27154MF Recombinant Full Length Macaca Fascicularis Natural Cytotoxicity Triggering Receptor 3(Ncr3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-176)
Pan troglodytes (Chimpanzee) RFL12024PF Recombinant Full Length Pan Troglodytes Natural Cytotoxicity Triggering Receptor 3(Ncr3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (19-201)
Rhesus Macaque NCR3-2961R Recombinant Rhesus monkey NCR3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NCR3-2780R Recombinant Rhesus Macaque NCR3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NCR3-2780R-B Recombinant Rhesus Macaque NCR3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NCR3 Related Research Area

NCR3 involved in several pathways and played different roles in them. We selected most pathways NCR3 participated on our site, such as Natural killer cell mediated cytotoxicity, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Natural killer cell mediated cytotoxicityITGB2;ICAM2;TYROBP;Raet1a;Raet1c;BRAF;PLCG1;VAV2;MICB

NCR3 has several biochemical functions, for example, cell adhesion molecule binding, protein homodimerization activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NCR3 itself. We selected most functions NCR3 had, and list some proteins which have the same functions with NCR3. You can find most of the proteins on our site.

Function Related Protein
cell adhesion molecule bindingVCAM1;NLGN3;GLYCAM1;FGFR1;ITGAL;NCR3;PVRL1B;CRTAM;SMAGP
protein homodimerization activityTLR13;GABRR1;MCL1A;PLEKHB1;LRP6;TRIM9;MAP3K12;PVRL2;CPOX
receptor activityLILRB3;CADM1A;GRIN2BB;NLGN2;FPR1;TNFRSF17;IL18RAP;GRIA4B;BTLA
receptor bindingPTK2AB;DVL3;TNFSF9;PVRL3;AMH;FRK;PVRL2;CALCA;LTB

NCR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCR3.

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can NCR3 be used for personalized medicine? 08/21/2022

The study of NCR3 expression and genetic variations may help tailor treatments for individuals with certain diseases, making it a potential component of personalized medicine.

How is NCR3 protein linked to inflammatory bowel disease (IBD)? 10/11/2021

NCR3 is implicated in the pathogenesis of IBD, and drugs targeting this protein may offer new therapeutic options for patients with IBD.

How does NCR3 relate to autoimmune diseases? 09/10/2020

NCR3 dysfunction has been associated with autoimmune diseases, and understanding its role may lead to new therapies.

Are there any challenges associated with NCR3-based therapies? 06/02/2019

Challenges include potential side effects, limited understanding of NCR3 in some diseases, and the need for further clinical validation.

Are there any clinical trials involving NCR3 protein? 08/31/2018

Yes, clinical trials are exploring NCR3-based immunotherapies for various cancers and infectious diseases.

Customer Reviews (3)

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Reviews
02/01/2022

    Choosing the NCR3 protein from this manufacturer not only provides me with a superior product but also grants me access to unparalleled technical support.

    12/16/2020

      The manufacturer's commitment to customer satisfaction is unmatched.

      01/13/2016

        The manufacturer's commitment to customer satisfaction and their willingness to customize solutions based on specific experimental requirements is commendable.

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