Recombinant Human NCR3, His-tagged
Cat.No. : | NCR3-5087H |
Product Overview : | Recombinant human NCR3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | NCR3, also known as NKP30, is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5" untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 15.3 kDa (141aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MLWVSQPPEI RTLEGSSAFL PCSFNASQGR LAIGSVTWFR DEVVPGKEVR NGTPEFRGRL APLASSRFLH DHQAELHIRD VRGHDASIYV CRVEVLGLGV GTGNGTRLVV EKEHPQLGAG T |
Purity : | >90% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Gene Name : | NCR3 natural cytotoxicity triggering receptor 3 [ Homo sapiens ] |
Official Symbol : | NCR3 |
Synonyms : | NCR3; natural cytotoxicity triggering receptor 3; LY117, lymphocyte antigen 117; 1C7; CD337; NKp30; NK-p30; lymphocyte antigen 117; activating NK-A1 receptor; activating natural killer receptor p30; natural killer cell p30-related protein; MALS; LY117; |
Gene ID : | 259197 |
mRNA Refseq : | NM_001145466 |
Protein Refseq : | NP_001138938 |
MIM : | 611550 |
UniProt ID : | O14931 |
Chromosome Location : | 6p21.3 |
Pathway : | Natural killer cell mediated cytotoxicity, organism-specific biosystem; Natural killer cell mediated cytotoxicity, conserved biosystem; |
Function : | receptor activity; |
Products Types
◆ Recombinant Protein | ||
NCR3-399H | Recombinant Human NCR3 Protein, Fc-tagged | +Inquiry |
NCR3-044H | Recombinant Human NCR3 Protein, C-His-tagged | +Inquiry |
NCR3-498C | Active Recombinant Cynomolgus NCR3 Protein, His-tagged | +Inquiry |
NCR3-2780R | Recombinant Rhesus Macaque NCR3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NCR3-256H | Recombinant Human NCR3 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
NCR3-2652HCL | Recombinant Human NCR3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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