Thiazovivin, GMP Grade

• Cat.No.: Thiazovivin-19
• Product Overview: Thiazovivin (GMP) is Thiazovivin produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.

Specification

• Description: Thiazovivin is a potent ROCK inhibitor.
• Form: Solid, White to light yellow
• Target: ROCK
• In Vitro: Thiazovivin (GMP) (0.5 μM, at 1 day) promotes rapid and efficient reprogramming of mouse tail tip and embryonic fibroblasts into iPSCs. Thiazovivin (GMP) enhances the efficiency in reprograming endometrial adult stromal cells to iPSCs. Thiazovivin (GMP) (2 μM) induces iPSCs and induced neural stem cells (iNSCs) from human urine cells (UCs). Thiazovivin (GMP) (2 μM, for the first 24 h) improves growth rate of hiPSCs. Thiazovivin (GMP) (0.5 μM) together with SB431542 and PD0325901 promotes iPSC reprogramming by regulating cell-cell interactions.
• CAS: 1226056-71-8
• Formula: C15H13N5OS
• Molecular Mass: 311.36
• Storage: 4 centigrade, sealed storage, away from moisture and light

Gene Information

• Pathway: Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
• Synonyms: Thiazovivin