Y-27632 dihydrochloride, GMP Grade

• Cat.No.: Y-27632 dihydrochloride-06
• Product Overview: Y-27632 dihydrochloride (GMP) is the GMP level of Y-27632 dihydrochloride. GMP guidelines are used to produce Y-27632 dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture.

Specification

• Description: Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor with antiepileptic effect.
• Form: Powder, White to off-white
• Target: ROCK
• In Vitro: Y-27632 dihydrochloride (GMP) (2 μM; 4-8 days) increases the survival rate and enhances reprogramming of mouse fibroblasts directly converted into neuronal cells. Y-27632 dihydrochloride (GMP) induces the conversion of human fibroblasts into functional cardiomyocytes. Y-27632 dihydrochloride (GMP) induces the conversion of fibroblasts into human induced pluripotent stem cells (hiPSCs). Y-27632 dihydrochloride (GMP) (2-10 μM) promotes the proliferation of human EPS cells and induces the conversion of primed hPSCs into hEPS cells. Y-27632 dihydrochloride (GMP) (10 μM) induces human EPS cells derived from blastocysts.
• Solubility Data: H2O: 100 mg/mL (312.25 mM; Need ultrasonic)
• CAS: 129830-38-2
• Formula: C14H23Cl2N3O
• Molecular Mass: 320.26
• Storage: At -20 centigrade, sealed storage, away from moisture and light.
• Shipping: Shipping with dry ice.

Gene Information

• Pathway: Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
• Synonyms: Y-27632 dihydrochloride