Description : |
A 83-01 is a potent ALK4/5/7 inhibitor |
Form : |
Solid, White to off-white |
Target : |
Anaplastic lymphoma kinase (ALK) |
In Vitro : |
A 83-01 (GMP) induces human foreskin fibroblasts converts into ardiomyocyte-like cells a more open-chromatin conformation at key heart developmental genes.
A 83-01 (GMP) induces cord blood or fetal liver-derived CD34+ cells converts into pluripotent cells. |
In Vivo : |
A 83-01 (GMP) (human foreskin fibroblast with aMHC-GFP; incubates in vitro 6 days than transplanted into the infarcted hearts of immunodeficient mice) induces fibroblasts converts into cardiomyocyte-like cells in infarcted mouse heart |
CAS : |
909910-43-6 |
Formula : |
C25H19N5S |
Molecular Mass : |
421.52 |
Storage : |
At -20 centigrade, protect from light |
Shipping : |
Shipping with dry ice. |