Active GMP Recombinant Human BDNF Protein

• Cat.No.: BDNF-01HG
• Product Overview: Recombinant human BDNF protein, was expressed in CHO-K1 cell-derived in an animal component free process under cGMP guidelines.

Specification

• Description: This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
• Source: CHO-K1
• Species: Human
• Form: Lyophilized powder
• Endotoxin: <20 EU/mg
• Bio-activity: > 5.0 x 10^5 IU/mg
• Purity: >95.0% by high performance liquid chromatography (SEC-HPLC) and SDS-PAGE.
• Storage Buffer: 10mM Phosphate-Buffered Saline (pH 7.2)
• Storage: Stable storage at 4℃ for 7-10 days; for long-term storage, please store at -20℃ after dispensing.
• Sterility: Sterility
• Instructions: It is recommended that lyophilized GMP rhBDNF be dissolved in water for injection or sterilized ultrapure water at a concentration of not less than 100 μg/ml, pending further dilution to working concentration.

Gene Information

• Gene Name: BDNF brain derived neurotrophic factor [ Homo sapiens (human) ]
• Official Symbol: BDNF
• Synonyms: ANON2; BULN2
• Gene ID: 627
• mRNA Refseq: NM_001143805.1
• Protein Refseq: NP_001137277.1
• UniProt ID: P23560
• MIM: 113505