| Species : |
Human |
| Source : |
CHO |
| Description : |
GM-CSF can act on hematopoietic stem cells and promote their differentiation and proliferation, while the cells formed are not limited to the neutrophil and monocyte-phagocyte systems. In vitro experimental studies revealed that with increasing GM-CSF concentration, proliferation of mononuclear macrophages was first stimulated, followed by neutrophils and finally eosinophils and megakaryocytes. In addition GM-CSF also stimulates the proliferation and differentiation of pluripotent stem cells and early erythroid cells. |
| Form : |
Lyophilized powder |
| Endotoxin : |
<20 EU/mg |
| Bio-activity : |
>1.0 x 10^6 IU/mg |
| Purity : |
>98.0% by high performance liquid chromatography (SEC-HPLC) and SDS-PAGE. |
| Storage Buffer : |
10mM Phosphate-Buffered Saline (pH 7.2) |
| Storage : |
Stable storage at 4℃ for 7-10 days; for long-term storage, please store at -20℃ after dispensing. |
| Sterility : |
Sterility |
| Instructions : |
It is recommended that lyophilized GMP rhGM-CSF be dissolved in water for injection or sterilized ultrapure water at a concentration of not less than 100 μg/ml, pending further dilution to working concentration. |
