Active Human CCL16
Cat.No. : | CCL16-112H |
Product Overview : | It is a synthetic Protein |
- Specification
- Gene Information
- Related Products
Description : | NCC-4 (also known as HCC-4) is a CC chemokine. It is a 97 amino acid protein. It exhibits less than 30% sequence identity to other CC chemokines. NCC-4 chemoattracts human monocytes and THP-1 cells. However it does not chemoattract resting lymphocytes or neutrophils. It has been found to supress proliferation of myeloid progenitor cells and induces calcium flux in THP-1 cells. This calcium flux can be desensitized by exposure to RANTES which suggests that NCC-4 and RANTES share the same receptor in THP-1 cells. |
Species : | Human |
Form : | Lyophilized |
Bio-activity : | Activity measured by the protein's ability to chemoattract THP-1 cells. ED50 for this activity is 0.5-3 μg/ml. |
Applications : | Activity Assay |
Storage : | Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles |
Reconstitution : | Recommended reconstitution in sterile phosphate buffered saline which contains at least 0.1% human or bovine serum albumin to prepare a stocksolution of no less than 20 μg/ml and vortex thoroughly. |
Gene Name : | CCL16 chemokine (C-C motif) ligand 16 [ Homo sapiens ] |
Official Symbol : | CCL16 |
Synonyms : | CCL16; chemokine (C-C motif) ligand 16; SCYA16, small inducible cytokine subfamily A (Cys Cys), member 16; C-C motif chemokine 16; CKb12; HCC 4; LCC 1; LEC; LMC; Mtn 1; NCC 4; SCYL4; monotactin-1; chemokine LEC; chemokine CC-4; new CC chemokine 4; liver CC chemokine-1; IL-10-inducible chemokine; liver-expressed chemokine; small-inducible cytokine A16; lymphocyte and monocyte chemoattractant; small inducible cytokine subfamily A (Cys-Cys), member 16; NCC4; HCC-4; LCC-1; Mtn-1; NCC-4; ILINCK; SCYA16; MGC117051; |
Gene ID : | 6360 |
mRNA Refseq : | NM_004590 |
Protein Refseq : | NP_004581 |
MIM : | 601394 |
UniProt ID : | O15467 |
Chromosome Location : | 17q11.2 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem; |
Function : | chemoattractant activity; chemokine activity; |
Products Types
◆ Recombinant Protein | ||
CCL16-113C | Active Recombinant Human CCL16 Protein (97 aa) | +Inquiry |
CCL16-268C | Active Recombinant Human CCL16 Protein (97 aa) | +Inquiry |
CCL16-0613H | Recombinant Human CCL16 Protein, GST-Tagged | +Inquiry |
CCL16-1014H | Recombinant Human CCL16 Protein (Gln24-Gln120), N-GST tagged | +Inquiry |
CCL16-151H | Recombinant Human CCL16 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CCL16-7730HCL | Recombinant Human CCL16 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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