Active Human CCL16 CCL16-112H

Active Human CCL16

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Active Human CCL16

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Specification Gene Information Related Products
Cat.No. : CCL16-112H Optional Service: Optional requirements on this protein
Product Overview : It is a synthetic Protein
Description : NCC-4 (also known as HCC-4) is a CC chemokine. It is a 97 amino acid protein. It exhibits less than 30% sequence identity to other CC chemokines. NCC-4 chemoattracts human monocytes and THP-1 cells. However it does not chemoattract resting lymphocytes or neutrophils. It has been found to supress proliferation of myeloid progenitor cells and induces calcium flux in THP-1 cells. This calcium flux can be desensitized by exposure to RANTES which suggests that NCC-4 and RANTES share the same receptor in THP-1 cells.
Species : Human
Form : Lyophilized
Bio-activity : Activity measured by the protein's ability to chemoattract THP-1 cells. ED50 for this activity is 0.5-3 μg/ml.
Applications : Activity Assay
Storage : Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
Reconstitution : Recommended reconstitution in sterile phosphate buffered saline which contains at least 0.1% human or bovine serum albumin to prepare a stocksolution of no less than 20 μg/ml and vortex thoroughly.
Gene Name : CCL16 chemokine (C-C motif) ligand 16 [ Homo sapiens ]
Official Symbol : CCL16
Synonyms : CCL16; chemokine (C-C motif) ligand 16; SCYA16, small inducible cytokine subfamily A (Cys Cys), member 16; C-C motif chemokine 16; CKb12; HCC 4; LCC 1; LEC; LMC; Mtn 1; NCC 4; SCYL4; monotactin-1; chemokine LEC; chemokine CC-4; new CC chemokine 4; liver CC chemokine-1; IL-10-inducible chemokine; liver-expressed chemokine; small-inducible cytokine A16; lymphocyte and monocyte chemoattractant; small inducible cytokine subfamily A (Cys-Cys), member 16; NCC4; HCC-4; LCC-1; Mtn-1; NCC-4; ILINCK; SCYA16; MGC117051;
Gene ID : 6360
mRNA Refseq : NM_004590
Protein Refseq : NP_004581
MIM : 601394
UniProt ID : O15467
Chromosome Location : 17q11.2
Pathway : Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (i) signalling events, organism-specific biosystem;
Function : chemoattractant activity; chemokine activity;

Products Types

◆ Recombinant Protein

CCL16-113CRecombinant Human CCL16 Protein (97 aa)+Inquiry
CCL16-0613HRecombinant Human CCL16 Protein, GST-Tagged+Inquiry
CCL16-268CRecombinant Human CCL16 Protein (97 aa)+Inquiry
CCL16-296HRecombinant Human CCL16, StrepII-tagged+Inquiry
CCL16-352HActive Recombinant Human CCL16, HIgG1 Fc-tagged, mutant+Inquiry

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◆ Lysates

CCL16-7730HCLRecombinant Human CCL16 293 Cell Lysate+Inquiry

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Related Gene

CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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