Active Native Human a-Macroglobulin
| Cat.No. : | a-Macroglobulin-535H |
| Product Overview : | Native Human a-Macroglobulin was purified from human plasma. |
- Specification
- Gene Information
- Related Products
| Description : | alpha-2-Macroglobulin, also known as α2-macroglobulin and abbreviated as α2M and A2M, is a large plasma protein found in the blood. It is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. |
| Source : | human plasma |
| Species : | Human |
| Form : | Lyophilized from 0.02 M Tris, 0.13 M glycine, pH 8.0, and 0.08 M trehalose |
| Bio-activity : | This product is a preparation of the intact protein with proteolytic inhibitory activity. One mg of protein will inhibit a minimum of 10 mg of trypsin with an activity of 10,000 BAEE units/mg protein. |
| Molecular Mass : | mol wt ~720 kDa (four glycoprotein subunits) |
| Purity : | ≥98% (SDS-PAGE) |
| Applications : | Inhibits all classes of endoproteases by forming a complex with the protease. When the protease cleaves the macroglobulin sequence, the macroglobulin rearranges and traps the protease. |
| Notes : | Plasma from each donor has been tested and found negative for antibody to HIV-1/HIV-2, antibody to HCV and HbSAg. |
| Storage : | The lyophilized powder is stable for at least 2 years when stored at -20 °C. |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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