Active Native Human ALPL Protein

• Cat.No.: ALPL-25H
• Product Overview: Native protein of human ALPL was derived from human placenta.

Specification

• Description: The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
• Source: Human placenta
• Species: Human
• Form: Liquid
• Bio-activity: 1069U/mg solid
  1000U/ml
  One unit liberates one micromole of p-nitrophenol per minute at 37 centigrade, pH 10.15 in Tris buffer.
• Purity: Biuret: 95%
• Applications: ELISA
• Notes: For research purposes only.
• Stability: Shelf Life: 12 months from date of despatch
• Storage: Store at -20 centigrade only. Storage in frost-free freezers is not recommended. This product should be stored undiluted.
• Storage Buffer: Phosphate buffered saline.

Gene Information

• Gene Name: ALPP
• Official Symbol: ALPP alkaline phosphatase, placental [ Homo sapiens (human) ]
• Synonyms: ALPP; alkaline phosphatase, placental; ALP; PALP; PLAP; PLAP-1; alkaline phosphatase, placental type; alkaline phosphatase Regan isozyme; alkaline phosphomonoesterase; glycerophosphatase; placental alkaline phosphatase 1; EC 3.1.3.1
• Gene ID: 250
• mRNA Refseq: NM_001632
• Protein Refseq: NP_001623
• MIM: 171800
• UniProt ID: P05187