Active Native Human Cathepsin H

• Cat.No.: CTSH-190H

Specification

• Species: Human
• Source: Human Liver
• Tag: Non
• Description: A more basic protein than Cathepsin B or L. Functions as both an aminopeptidase and endopeptidase. Cathepsin H, like cathepsin L and B, is involved in the catabolism of proteins in the lysosomal system.
• Form: Frozen
• Bio-activity: Greater than 1 unit per mg protein. One unit is de ned as the amount of enzyme which hydrolyzes one μmole of L-arginine-beta-naphtylamide per minute at 40°C in 75 mM potassium phosphate bu er, pH 6.8 with 1 mM EDTA and 3 mM cysteine.
• Molecular Mass: MW 28,000
• Purity: >= 95% by SDS-PAGE
• Usage: For research use only
• Quality Control Test: Shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
• Stability: >1 year
• Storage: <=>
• Storage Buffer: 20 mM Na Acetate, pH 4.5 with 1 mM EDTA and 100 mM NaCl

Gene Information

• Gene Name: CTSH cathepsin H [ Homo sapiens ]
• Official Symbol: CTSH
• Synonyms: CTSH; cathepsin H; CPSB; pro-cathepsin H; ACC 4; ACC 5; aleurain; cathepsin B3; cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase; ACC-4; ACC-5; minichain; MGC1519; DKFZp686B24257
• Gene ID: 1512
• mRNA Refseq: NM_004390
• Protein Refseq: NP_004381
• MIM: 116820
• UniProt ID: P09668
• Chromosome Location: 15q25.1
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem
• Function: HLA-A specific activating MHC class I receptor activity; aminopeptidase activity; apoptotic protease activator activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; endopeptidase activity; kininogen binding; peptidase activity; protein binding; serine-type endopeptidase activity; thyroid hormone binding