Active Native Staphylococcus aureus Sphingomyelinase

Species :	S.aureus
Source :	S. aureus
Description :	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine.
Bio-activity :	Specific activity: 100-300 U/mg protein. One unit will hydrolyze 1 μmol of TNPAL-sphingomyelin per minute at pH 7.4 and 37 centigrade.
Applications :	May be used exogenously to initiate the sphingomyelin signaling pathway. Has very little activity on phosphatidylcholine.
Storage :	At +4 centigrade
Storage Buffer :	Supplied in 50% glycerol/0.25 M phosphate buffer.
Shipping :	Blue Ice Not Frozen