Active Recombinant Full Length Human AQP3 Protein, C-Flag-tagged

• Cat.No.: AQP3-289HFL
• Product Overview: Recombinant Full Length Human AQP3 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes the water channel protein aquaporin 3. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0. Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney. In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree. It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: In vivo treatment
• Molecular Mass: 31.4 kDa
• AA Sequence: MGRQKELVSRCGEMLHIRYRLLRQA LAECLGTLILVMFGCGSVAQVVLSR GTHGGFLTINLAFGFAVTLG ILIAGQVSGAHLNPAVTFAMCFLAR EPWIKLPIYTLAQTLGAFLGAGIVF GLYYDAIWHFADNQLFVSGP NGTAGIFATYPSGHLDMINGFFDQF IGTASLIVCVLAIVDPYNNPVPRGL EAFTVGLVVLVIGTSMGFNS GYAVNPARDFGPRLFTALAGWGSAV FTTGQHWWWVPIVSPLLGSIAGVFV YQLMIGCHLEQPPPSNEEEN
  VKLAHVKHKEQITRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: AQP3 aquaporin 3 (Gill blood group) [ Homo sapiens (human) ]
• Official Symbol: AQP3
• Synonyms: GIL; AQP-3
• Gene ID: 360
• mRNA Refseq: NM_004925.5
• Protein Refseq: NP_004916.1
• MIM: 600170
• UniProt ID: Q92482