Active Recombinant Full Length Human CAPRIN1 Protein, C-Flag-tagged

• Cat.No.: CAPRIN1-283HFL
• Product Overview: Recombinant Full Length Human CAPRIN1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Co-immunoprecipitation
• Molecular Mass: 78.2 kDa
• AA Sequence: MPSATSHSGSGSKSSGPPPPSGSSG SEAAAGAGAAAPASQHPATGTGAVQ TEAMKQILGVIDKKLRNLEK KKGKLDDYQERMNKGERLNQDQLDA VSKYQEVTNNLEFAKELQRSFMALS QDIQKTIKKTARREQLMREE AEQKRLKTVLELQYVLDKLGDDEVR TDLKQGLNGVPILSEEELSLLDEFY KLVDPERDMSLRLNEQYEHA SIHLWDLLEGKEKPVCGTTYKVLKE IVERVFQSNYFDSTHNHQNGLCEEE EAASAPAVEDQVPEAEPEPA EEYTEQSEVESTEYVNRQFMAETQF TSGEKEQVDEWTVETVEVVNSLQQQ PQAASPSVPEPHSLTPVAQA DPLVRRQRVQDLMAQMQGPYNFIQD SMLDFENQTLDPAIVSAQPMNPTQN MDMPQLVCPPVHSESRLAQP NQVPVQPEATQVPLVSSTSEGYTAS QPLYQPSHATEQRPQKEPIDQIQAT ISLNTDQTTASSSLPAASQP QVFQAGTSKPLHSSGINVNAAPFQS MQTVFNMNAPVPPVNEPETLKQQNQ YQASYNQSFSSQPHQVEQTE LQQEQLQTVVGTYHGSPDQSHQVTG NHQQPPQQNTGFPRSNQPYYNSRGV SRGGSRGARGLMNGYRGPAN GFRGGYDGYRPSFSNTPNSGYTQSQ FSAPRDYSGYQRDGYQQNFKRGSGQ SGPRGAPRGRGGPPRPNRGM
  PQMNTQQVNTRTRPLEQKLISEEDL AANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: CAPRIN1 cell cycle associated protein 1 [ Homo sapiens (human) ]
• Official Symbol: CAPRIN1
• Synonyms: M11S1; GPIAP1; RNG105; GPIP137; GRIP137; p137GPI
• Gene ID: 4076
• mRNA Refseq: NM_005898.5
• Protein Refseq: NP_005889.3
• MIM: 601178
• UniProt ID: Q14444