Active Recombinant Full Length Human CARM1 Protein, Flag tagged

• Cat.No.: CARM1-10HFL
• Product Overview: Recombinant human PRMT4 (CARM1) was expressed in a baculovirus expression system as the full length protein (accession number NP_954592.1) with an N-terminal Flag tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag
• Protein Length: 1-608 aa
• Description: This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9.
• Molecular Mass: 66.8 kDa
• Purity: > 88%
• Application: Recombinant PRMT4 (CARM1) protein is suitable for use in enzyme kinetics, inhibitor screening, and selectivity profiling.
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• Storage Buffer: 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100 and 0.5 mM TCEP.

Gene Information

• Gene Name: CARM1 coactivator associated arginine methyltransferase 1 [ Homo sapiens (human) ]
• Official Symbol: CARM1
• Synonyms: CARM1; coactivator associated arginine methyltransferase 1; PRMT4; histone-arginine methyltransferase CARM1; protein arginine N-methyltransferase 4; EC 2.1.1.319
• Gene ID: 10498
• mRNA Refseq: NM_199141
• Protein Refseq: NP_954592
• MIM: 603934
• UniProt ID: Q86X55