Active Recombinant Full Length Human CCL5 Protein, C-Flag-tagged
Cat.No. : | CCL5-1068HFL |
Product Overview : | Recombinant Full Length Human CCL5 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Bio-activity : | Binding assay |
Molecular Mass : | 7.8 kDa |
AA Sequence : | MKVSAAALAVILIATALCAPASASP YSSDTTPCCFAYIARPLPRAHIKEY FYTSGKCSNPAVVFVTRKNRQVCAN PEKKWVREYINSLEMSTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways : | Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, NOD-like receptor signaling pathway, Prion diseases, Toll-like receptor signaling pathway |
Gene Name : | CCL5 C-C motif chemokine ligand 5 [ Homo sapiens (human) ] |
Official Symbol : | CCL5 |
Synonyms : | SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta |
Gene ID : | 6352 |
mRNA Refseq : | NM_002985.3 |
Protein Refseq : | NP_002976.2 |
MIM : | 187011 |
UniProt ID : | P13501 |
Products Types
◆ Recombinant Protein | ||
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CCL5-1397M | Recombinant Mouse CCL5 Protein, His (Fc)-Avi-tagged | +Inquiry |
CCL5-032H | Recombinant Human CCL5 Protein, Biotinylated | +Inquiry |
CCL5-1206C | Recombinant Cattle CCL5 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CCL5-2706HCL | Recombinant Human CCL5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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