Active Recombinant Full Length Human DNM1L Protein, C-Flag-tagged
Cat.No. : | DNM1L-199HFL |
Product Overview : | Recombinant Full Length Human DNM1L Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Bio-activity : | Cell treatment |
Molecular Mass : | 81.7 kDa |
AA Sequence : | MEALIPVINKLQDVFNTVGADIIQL PQIVVVGTQSSGKSSVLESLVGRDL LPRGTGIVTRRPLILQLVHV SQEDKRKTTGEENGVEAEEWGKFLH TKNKLYTDFDEIRQEIENETERISG NNKGVSPEPIHLKIFSPNVV NLTLVDLPGMTKVPVGDQPKDIELQ IRELILRFISNPNSIILAVTAANTD MATSEALKISREVDPDGRRT LAVITKLDLMDAGTDAMDVLMGRVI PVKLGIIGVVNRSQLDINNKKSVTD SIRDEYAFLQKKYPSLANRN GTKYLARTLNRLLMHHIRDCLPELK TRINVLAAQYQSLLNSYGEPVDDKS ATLLQLITKFATEYCNTIEG TAKYIETSELCGGARICYIFHETFG RTLESVDPLGGLNTIDILTAIRNAT GPRPALFVPEVSFELLVKRQ IKRLEEPSLRCVELVHEEMQRIIQH CSNYSTQELLRFPKLHDAIVEVVTC LLRKRLPVTNEMVHNLVAIE LAYINTKHPDFADACGLMNNNIEEQ RRNRLARELPSAVSRDKSSKVPSAL APASQEPSPAASAEADGKLI QDSRRETKNVASGGGGVGDGVQEPT TGNWRGMLKTSKAEELLAEEKSKPI PIMPASPQKGHAVNLLDVPV PVARKLSAREQRDCEVIERLIKSYF LIVRKNIQDSVPKAVMHFLVNHVKD TLQSELVGQLYKSSLLDDLL TESEDMAQRRKEAADMLKALQGASQ IIAEIRETHLWTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Pathways : | Endocytosis, Fc gamma R-mediated phagocytosis |
Gene Name : | DNM1L dynamin 1 like [ Homo sapiens (human) ] |
Official Symbol : | DNM1L |
Synonyms : | DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV |
Gene ID : | 10059 |
mRNA Refseq : | NM_012062.5 |
Protein Refseq : | NP_036192.2 |
MIM : | 603850 |
UniProt ID : | O00429 |
Products Types
◆ Recombinant Protein | ||
DNM1L-8494H | Recombinant Human DNM1L Protein, Myc/DDK-tagged | +Inquiry |
DNM1L-2584H | Recombinant Human DNM1L Protein (1-710 aa), His-Myc-tagged | +Inquiry |
Dnm1l-2618M | Recombinant Mouse Dnm1l Protein, Myc/DDK-tagged | +Inquiry |
DNM1L-1582R | Recombinant Rat DNM1L Protein, His (Fc)-Avi-tagged | +Inquiry |
DNM1L-8493H | Active Recombinant Human DNM1L Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
DNM1L-6858HCL | Recombinant Human DNM1L 293 Cell Lysate | +Inquiry |
DNM1L-6859HCL | Recombinant Human DNM1L 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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