Active Recombinant Full Length Human PFKP Protein, C-Flag-tagged

• Cat.No.: PFKP-284HFL
• Product Overview: Recombinant Full Length Human PFKP Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: Cell treatment
• Molecular Mass: 85.4 kDa
• AA Sequence: MDADDSRAPKGSLRKFLEHLSGAGK AIGVLTSGGDAQGMNAAVRAVVRMG IYVGAKVYFIYEGYQGMVDG GSNIAEADWESVSSILQVGGTIIGS ARCQAFRTREGRLKAACNLLQRGIT NLCVIGGDGSLTGANLFRKE WSGLLEELARNGQIDKEAVQKYAYL NVVGMVGSIDNDFCGTDMTIGTDSA LHRIIEVVDAIMTTAQSHQR TFVLEVMGRHCGYLALVSALACGAD WVFLPESPPEEGWEEQMCVKLSENR ARKKRLNIIIVAEGAIDTQN KPITSEKIKELVVTQLGYDTRVTIL GHVQRGGTPSAFDRILASRMGVEAV IALLEATPDTPACVVSLNGN HAVRLPLMECVQMTQDVQKAMDERR FQDAVRLRGRSFAGNLNTYKRLAIK LPDDQIPKTNCNVAVINVGA PAAGMNAAVRSAVRVGIADGHRMLA IYDGFDGFAKGQIKEIGWTDVGGWT GQGGSILGTKRVLPGKYLEE IATQMRTHSINALLIIGGFEAYLGL LELSAAREKHEEFCVPMVMVPATVS NNVPGSDFSIGADTALNTIT DTCDRIKQSASGTKRRVFIIETMGG YCGYLANMGGLAAGADAAYIFEEPF DIRDLQSNVEHLTEKMKTTI QRGLVLRNESCSENYTTDFIYQLYS EEGKGVFDCRKNVLGHMQQGGAPSP FDRNFGTKISARAMEWITAK LKEARGRGKKFTTDDSICVLGISKR NVIFQPVAELKKQTDFEHRIPKEQW WLKLRPLMKILAKYKASYDV
  SDSGQLEHVQPWSVSGPTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway

Gene Information

• Gene Name: PFKP phosphofructokinase, platelet [ Homo sapiens (human) ]
• Official Symbol: PFKP
• Synonyms: PFKF; PFK-C; PFK-P; ATP-PFK
• Gene ID: 5214
• mRNA Refseq: NM_002627.5
• Protein Refseq: NP_002618.1
• MIM: 171840
• UniProt ID: Q01813