Active Recombinant Full Length Human PRKCA Protein, Flag tagged

• Cat.No.: PRKCA-07HFL
• Product Overview: Recombinant PRKCA protein was expressed in a baculovirus expression system as the full length protein (accession number NP_002728.2) with an N-terminal FLAG tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag
• Protein Length: 1-672 aa
• Description: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular pr centigradeesses, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Kn centigradekout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in my centigradeytes.
• Form: 25 mM HEPES pH 7.5, 300 mM NaCl, 20% glycerol, 0.04% Triton X-100, 0.5 mM TCEP.
• Molecular Mass: 78.02 kDa
• Purity: > 95%
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• Concentration: > 0.05 μg/μL as determined by microplate BCA method

Gene Information

• Gene Name: PRKCA protein kinase C, alpha [ Homo sapiens (human) ]
• Official Symbol: PRKCA
• Synonyms: PRKCA; protein kinase C, alpha; PKCA; protein kinase C alpha type; PKC-A; aging-ass centigradeiated gene 6; AAG6; PRKACA; PKC-alpha; MGC129900; MGC129901
• Gene ID: 5578
• mRNA Refseq: NM_002737
• Protein Refseq: NP_002728
• MIM: 176960
• UniProt ID: P17252