Active Recombinant Full Length Human RAD18 Protein, C-Flag-tagged
Cat.No. : | RAD18-529HFL |
Product Overview : | Recombinant Full Length Human RAD18 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Bio-activity : | In vitro protein binding assay |
Molecular Mass : | 56 kDa |
AA Sequence : | MDSLAESRWPPGLAVMKTIDDLLRC GICFEYFNIAMIIPQCSHNYCSLCI RKFLSYKTQCPTCCVTVTEP DLKNNRILDELVKSLNFARNHLLQF ALESPAKSPASSSSKNLAVKVYTPV ASRQSLKQGSRLMDNFLIRE MSGSTSELLIKENKSKFSPQKEASP AAKTKETRSVEEIAPDPSEAKRPEP PSTSTLKQVTKVDCPVCGVN IPESHINKHLDSCLSREEKKESLRS SVHKRKPLPKTVYNLLSDRDLKKKL KEHGLSIQGNKQQLIKRHQE FVHMYNAQCDALHPKSAAEIVQEIE NIEKTRMRLEASKLNESVMVFTKDQ TEKEIDEIHSKYRKKHKSEF QLLVDQARKGYKKIAGMSQKTVTIT KEDESTEKLSSVCMGQEDNMTSVTN HFSQSKLDSPEELEPDREED SSSCIDIQEVLSSSESDSCNSSSSD IIRDLLEEEEAWEASHKNDLQDTEI SPRQNRRTRAAESAEIEPRN KRNRNTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Protein Families : | Druggable Genome |
Gene Name : | RAD18 RAD18 E3 ubiquitin protein ligase [ Homo sapiens (human) ] |
Official Symbol : | RAD18 |
Synonyms : | RNF73 |
Gene ID : | 56852 |
mRNA Refseq : | NM_020165.4 |
Protein Refseq : | NP_064550.3 |
MIM : | 605256 |
UniProt ID : | Q9NS91 |
Products Types
◆ Recombinant Protein | ||
Rad18-5347M | Recombinant Mouse Rad18 Protein, Myc/DDK-tagged | +Inquiry |
RAD18-1848H | Recombinant Human RAD18 Protein, His (Fc)-Avi-tagged | +Inquiry |
RAD18-1151H | Recombinant Human RAD18 Protein (1-495 aa), His-SUMO-tagged | +Inquiry |
RAD18-10488Z | Recombinant Zebrafish RAD18 | +Inquiry |
RAD18-2315C | Recombinant Chicken RAD18 | +Inquiry |
◆ Lysates | ||
RAD18-2561HCL | Recombinant Human RAD18 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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