Active Recombinant Full Length Mouse Mapk8 Protein, GST tagged
| Cat.No. : | Mapk8-338M |
| Product Overview : | Recombinant full-length mouse JNK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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| Species : | Mouse |
| Source : | Insect Cells |
| Tag : | GST |
| Protein Length : | 1-464 aa |
| Description : | Enables JUN kinase activity and protein serine/threonine/tyrosine kinase activity. Involved in several processes, including generation of neurons; integrin-mediated signaling pathway; and positive regulation of protein metabolic process. Acts upstream of or within several processes, including cellular response to nitric oxide; positive regulation of determination of dorsal identity; and protein phosphorylation. Located in several cellular components, including basal dendrite; mitochondrion; and podosome. Is active in Schaffer collateral - CA1 synapse and cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skin. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm; chronic mucocutaneous candidiasis; colorectal adenoma; rectal benign neoplasm; and type 2 diabetes mellitus. Orthologous to human MAPK8 (mitogen-activated protein kinase 8). |
| Molecular Mass : | 70 kDa |
| Bio-activity : | 105 nmol/min/mg |
| Purity : | The purity of JNK1 was determined to be >90% by densitometry. |
| Stability : | One year at –70 centigrade from date of shipment. |
| Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Storage Buffer : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Concentration : | 0.1 μg/μL |
| Shipping : | Dry ice |
| Gene Name | Mapk8 mitogen-activated protein kinase 8 [ Mus musculus (house mouse) ] |
| Official Symbol | Mapk8 |
| Synonyms | Mapk8; mitogen-activated protein kinase 8; JNK; JNK1; Prkm8; SAPK1; mitogen-activated protein kinase 8; JNK1 beta1 protein kinase; MAP kinase 8; MAPK 8; c-Jun N-terminal kinase 1; protein kinase mitogen-activated 8; stress-activated protein kinase JNK1; EC 2.7.11.24 |
| Gene ID | 26419 |
| mRNA Refseq | NM_016700 |
| Protein Refseq | NP_057909 |
| UniProt ID | Q61831 |
Not For Human Consumption!
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