Active Recombinant Human AMIGO3 Protein, Fc tagged

• Cat.No.: AMIGO3-22H
• Product Overview: Active Recombinant Human AMIGO3 Protein(Thr20-Pro378) with Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Chinese Hamster Ovary cell line.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Description: Predicted to be involved in brain development; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and positive regulation of synapse assembly. Predicted to be active in membrane.
• Form: Lyophilized
• Bio-activity: Measured by its ability to inhibit IL-2 secretion by mouse T cells in the presence of anti-CD3. The ED50 for this effect is 1-5 μg/mL.
• Molecular Mass: 66 kDa
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
• Storage: 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature.
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• N-terminal Sequence Analysis: Thr20
• Storage Buffer: Disulfide-linked homodimer. Lyophilized from a 0.2 μm filtered solution in PBS.

Gene Information

• Gene Name: AMIGO3 adhesion molecule with Ig-like domain 3 [ Homo sapiens (human) ]
• Official Symbol: AMIGO3
• Synonyms: AMIGO3; adhesion molecule with Ig-like domain 3; amphoterin-induced protein 3; amphoterin induced gene and open reading frame 3; alivin-3; amphoterin-induced gene and ORF 3; AMIGO-3; MGC120552
• Gene ID: 386724
• mRNA Refseq: NM_198722
• Protein Refseq: NP_942015
• MIM: 615691
• UniProt ID: Q86WK7