Active Recombinant Human BMP4/BMP7 protein

Species :	Human
Source :	E.coli
Tag :	Non
Protein Length :	BMP4(Ser293-Arg408)/BMP7(Ser293-His431)
Predicted N Terminal :	Met (BMP-4) & Ser293 (BMP-7)
Form :	Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Bio-activity :	Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351. The ED50 for this effect is typically 15-75 ng/mL.
Molecular Mass :	Predicted Molecular Mass: 13.3 (BMP-4), 15.8 (BMP-7) kDa
Endotoxin :	<0.01 EU per 1 μg of the protein by the LAL method.
Purity :	>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage :	Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution :	Reconstitute at 100 μg/mL in sterile 4 mM HCl.
Shipping :	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Gene Name	BMP4 bone morphogenetic protein 4 [ Homo sapiens ]
Official Symbol	BMP4
Synonyms	BMP4; bone morphogenetic protein 4; BMP2B; BMP-4; BMP-2B; bone morphogenetic protein 2B; ZYME; OFC11; BMP2B1; MCOPS6;
Gene ID	652
mRNA Refseq	NM_001202
Protein Refseq	NP_001193
MIM	112262
UniProt ID	P12644
Chromosome Location	14q22-q23
Pathway	Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Glypican 3 network, organism-specific biosystem; Heart Development, organism-specific biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem;
Function	BMP receptor binding; chemoattractant activity; cytokine activity; growth factor activity; protein binding;