Active Recombinant Human CADM4, Fc-tagged
Cat.No. : | CADM4-651H |
Product Overview : | The recombinant human NECL4-Fc fusion protein is expressed as a 532-amino acid protein consisting of Pro21 - Ala324 region of NECL4 (UniProt accession #Q8NFZ8) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
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Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). |
Bio-activity : | Immobilized NECL4 interact heterophilically with NECL1 and NECL3. Enhances neurite outgrowth of E16-E18 rat embryonic cortical neurons. |
Molecular Mass : | Calculated molecular mass (kDa): 59.0; Estimated by SDS-PAGE under reducing condition (kDa): 75-85 |
AA Sequence : | PGAGQEVQTENVTVAEGGVAEITCR LHQYDGSIVVIQNPARQTLFFNGTR ALKDERFQLEEFSPRRVRIRLSDA RLEDEGGYFCQLYTEDTHHQIATLT VLVAPENPVVEVREQAVEGGEVELS CLVPRSRPAATLRWYRDRKELKGV SSSQENGKVWSVASTVRFRVDRKDD GGIIICEAQNQALPSGHSKQTQYVL DVQYSPTARIHASQAVVREGDTLV LTCAVTGNPRPNQIRWNRGNESLPE RAEAVGETLTLPGLVSADNGTYTCE ASNKHGHARALYVLVVYDPGAVVE AQTSVPYASTGTHTCPPCPAPELLG GPSVFLFPPKPKDTLMISRTPEVTC VVVDVSHEDPEVKFNWYVDGVEVH NAKTKPREEQYNSTYRVVSVLTVLH QDWLNGKEYKCKVSNKALPAPIEKT ISKAKGQPREPQVYTLPPSREEMT KNQVSLTCLVKGFYPSDIAVEWESN GQPENNYKTTPPVLDSDGSFFLYSK LTVDKSRWQQGNVFSCSVMHEALH NHYTQKSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Protein length : | Pro21-Ala324 |
Gene Name : | CADM4 cell adhesion molecule 4 [ Homo sapiens ] |
Official Symbol : | CADM4 |
Synonyms : | CADM4; cell adhesion molecule 4; IGSF4C, immunoglobulin superfamily, member 4C; Necl 4; nectin like 4; SynCAM4; TSLL2; TSLC1-like 2; nectin-like 4; TSLC1-like protein 2; nectin-like protein 4; immunoglobulin superfamily member 4C; immunoglobulin superfamily, member 4C; NECL4; IGSF4C; Necl-4; synCAM4; |
Gene ID : | 199731 |
mRNA Refseq : | NM_145296 |
Protein Refseq : | NP_660339 |
MIM : | 609744 |
UniProt ID : | Q8NFZ8 |
Chromosome Location : | 19q13.32 |
Products Types
◆ Recombinant Protein | ||
Cadm4-1933M | Recombinant Mouse Cadm4 Protein, Myc/DDK-tagged | +Inquiry |
CADM4-746R | Recombinant Rat CADM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Cadm4-6879M | Recombinant Mouse Cadm4 protein(Met1-Ala324), His-tagged | +Inquiry |
CADM4-2298H | Recombinant Human CADM4 Protein, MYC/DDK-tagged | +Inquiry |
CADM4-747H | Recombinant Human CADM4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CADM4-1838MCL | Recombinant Mouse CADM4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Write a reviewReliable recombinant proteins are a must for researchers.
These product simplify our research.
Our lab relies on the product for consistency.
Q&As (5)
Ask a questionImmunoprecipitation allows the isolation of CADM4 and its binding partners, helping identify proteins that interact with CADM4 and revealing its functional associations.
Cadm4's interactions extend beyond cell adhesion to impact intracellular signaling pathways. Through its adhesive properties, Cadm4 can initiate signaling events that influence cell proliferation, differentiation, and other cellular processes, making it an integral component of cellular signaling networks.
Cadm4 has a complex molecular structure involving extracellular domains for adhesion. It interacts with various proteins and ligands, facilitating cell adhesion and signaling.
Cadm4 expression varies during development and contributes to tissue development and cellular differentiation, particularly in the nervous system.
The development of Cadm4-targeted therapies faces challenges related to precision and effectiveness. Ongoing research is focused on refining drug targeting strategies and gaining a deeper understanding of Cadm4's relevance in various disease contexts.
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