Active Recombinant Human CASP4 Protein
Cat.No. : | CASP4-01H |
Product Overview : | Recombinant Human CASP4 Protein without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. |
Source : | E. coli |
Species : | Human |
Form : | Liquid |
Bio-activity : | Activity: 100 U/μL Specific Activity: One U=1 pmol/min at 30 centigrade using Ac-LEHD-pNA as substrate. |
Molecular Mass : | 19 + 10 kDa |
Purity : | >90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain. |
Storage : | At -80 centigrade. |
Storage Buffer : | In 50mM HEPES, pH 7.4, 100mM NaCl, 0.5% CHAPS, 1mM EDTA, 10% glycerol, 10mM DTT. |
Shipping : | Dry Ice |
Gene Name : | CASP4 caspase 4 [ Homo sapiens (human) ] |
Official Symbol : | CASP4 caspase 4 [ Homo sapiens (human) ] |
Synonyms : | CASP4; caspase 4; TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II; caspase-4; CASP-4; ICE and Ced-3 homolog 2; ICE(rel)-II; apoptotic cysteine protease Mih1/TX; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; protease ICH-2; protease TX; EC 3.4.22.57 |
Gene ID : | 837 |
mRNA Refseq : | NM_001225 |
Protein Refseq : | NP_001216 |
MIM : | 602664 |
UniProt ID : | P49662 |
Products Types
◆ Recombinant Protein | ||
Casp4-626R | Recombinant Rat Casp4 Protein, His-tagged | +Inquiry |
CASP4-0424H | Recombinant Human CASP4 Protein, GST-Tagged | +Inquiry |
CASP4-2594H | Recombinant Human CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP4-462R | Recombinant Rhesus Macaque CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CASP4-1244M | Recombinant Mouse CASP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CASP4-7836HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
CASP4-7837HCL | Recombinant Human CASP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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