Active Recombinant Human CCL7, biotinylated
| Cat.No. : | CCL7-132H |
| Product Overview : | Recombinant human CCL7 is produced in E. coli, biotinylated |
- Specification
- Gene Information
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| Description : | CCL7, also known as Monocyte Chemotactic Protein-3 (MCP-3), is a secreted chemokine that attracts macrophages, monocytes, and eosinophils during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. In vivo, this protein is a substrate of matrix metalloproteinase 2 (MMP2), an enzyme that degrades components of the extracellular matrix. The gene that encodes CCL7 is part of a cluster of C-C chemokine family members on chromosome 17q. CCL7 binds to CCR1, CCR2, and CCR3 receptors and appears to be an antagonist for the CCR5 receptor. |
| Source : | E. coli |
| Species : | Human |
| Tag : | Biotin |
| Form : | Lyophilized. |
| Bio-activity : | EC50 = 1.4-2.6nM determined by migration of recombinant CCR2-expressing cells. |
| Molecular Mass : | 11.2kDa by Mass Spec |
| AA Sequence : | QPVGINTSTTCCYRFINKKIPKQRL ESYRRTTSSHCPREAVIFKTKLDKE ICADPTQKWVQDFMKHLDKKTQTPK LKLGSGLNDIFEAQKIEWHE |
| Endotoxin : | <0.01 EU per 1ug of protein by LAL method. |
| Purity : | >97% by SDS-PAGE |
| Storage : | 12 months from date of receipt, -20°C to -70°C, as supplied. 1 month, 2°C to 8°C, under sterile conditions after reconstitution. 3 months, -20°C to -70°C, under sterile conditions after reconstitution. |
| Reconstitution : | Recommended at 100ug/ml in sterile distilled water. |
| Gene Name : | CCL7 chemokine (C-C motif) ligand 7 [ Homo sapiens ] |
| Official Symbol : | CCL7 |
| Synonyms : | CCL7; chemokine (C-C motif) ligand 7; FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7; MGC138463; MGC138465; monocyte chemotactic protein 3; monocyte chemoattractant protein 3; small inducible cytokine A7 |
| Gene ID : | 6354 |
| mRNA Refseq : | NM_006273 |
| Protein Refseq : | NP_006264 |
| MIM : | 158106 |
| UniProt ID : | P80098 |
| Chromosome Location : | 17q11.2-q12 |
| Pathway : | Chemokine signaling pathway; Cytokine-cytokine receptor interaction |
| Function : | chemokine activity; heparin binding |
Products Types
| ◆ Recombinant Protein | ||
| Ccl7-2041M | Active Recombinant Mouse Ccl7 Protein | +Inquiry |
| CCL7-32M | Active Recombinant Mouse CCL7 Protein | +Inquiry |
| CCL7-0643H | Recombinant Human CCL7 Protein, GST-Tagged | +Inquiry |
| Ccl7-002M | Active Recombinant Mouse Ccl7 Protein | +Inquiry |
| CCL7-025H | Recombinant Human CCL7 Protein | +Inquiry |
| ◆ Lysates | ||
| CCL7-170HCL | Recombinant Human CCL7 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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