Active Recombinant Human CD14 protein

• Cat.No.: CD14-264H
• Product Overview: Recombinant Human CD14(Thr20-Cys352) was expressed in CHO.

Specification

• Species: Human
• Source: CHO
• Tag: Non
• Protein Length: Thr20-Cys352
• Description: The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein.
• Form: 1 x PBS, pH7.2
• Bio-activity: The ED50 is 100-400 ng/ml, corresponding to a specific activity of 1.0-2.5 x 104 units/mg, determined by production of IL-8 from THP-1 cells trated with LPS (2 ng/ml) and CD14.
• Molecular Mass: 35.8 kDa
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method.
• Purity: >95%, as determined by Coomassie stained SDS-PAGE.
• Concentration: Protein formulated and vialed at >50 ug/mL in specified buffer

Gene Information

• Gene Name: CD14 CD14 molecule [ Homo sapiens ]
• Official Symbol: CD14
• Synonyms: CD14; CD14 molecule; CD14 antigen; monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
• Gene ID: 929
• mRNA Refseq: NM_000591
• Protein Refseq: NP_000582
• MIM: 158120
• UniProt ID: P08571