Active Recombinant Human CD46 protein, hFc-tagged
Cat.No. : | CD46-0381H |
Product Overview : | Recombinant Human CD46 protein(P15529)(35-328aa), fused to C-terminal hFc tag, was expressed in Mammalian cell. |
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Source : | Mammalian cell |
Species : | Human |
Tag : | Fc |
Form : | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized CD46 at 2 μg/ml can bind Anti-CD46 rabbit monoclonal antibody, the EC50 of human CD46 protein is 0.8333-1.054 ng/ml. |
Molecular Mass : | 61.6 kDa |
Protein length : | 35-328aa |
AA Sequence : | CEEPPTFEAMELIGKPKPYYEIGER VDYKCKKGYFYIPPLATHTICDRNH TWLPVSDDACYRETCPYIRDPLNGQ AVPANGTYEFGYQMHFICNEGYYLI GEEILYCELKGSVAIWSGKPPICEK VLCTPPPKIKNGKHTFSEVEVFEYL DAVTYSCDPAPGPDPFSLIGESTIY CGDNSVWSRAAPECKVVKCRFPVVE NGKQISGFGKKFYYKATVMFECDKG FYLDGSDTIVCDSNSTWDPPVPKCL KVLPPSSTKPPALSHSVSTSSTTKS PASSASGPRPTYKPPVSNY |
Endotoxin : | Less than 1.0 EU/ug as determined by LAL method. |
Purity : | Greater than 92% as determined by SDS-PAGE. |
Storage : | Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. |
Gene Name : | CD46 CD46 molecule, complement regulatory protein [ Homo sapiens ] |
Official Symbol : | CD46 |
Synonyms : | CD46; CD46 molecule, complement regulatory protein; antigen identified by monoclonal TRA 2 10 , CD46 antigen, complement regulatory protein , MCP, membrane cofactor protein (CD46, trophoblast lymphocyte cross reactive antigen) , MIC10; membrane cofactor protein; MGC26544; TLX; TRA2.10; measles virus receptor; complement membrane cofactor protein; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; CD46 antigen, complement regulatory protein; trophoblast-lymphocyte cross-reactive antigen; antigen identified by monoclonal TRA-2-10; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); MCP; AHUS2; MIC10; |
Gene ID : | 4179 |
mRNA Refseq : | NM_002389 |
Protein Refseq : | NP_002380 |
MIM : | 120920 |
UniProt ID : | P15529 |
Products Types
◆ Recombinant Protein | ||
CD46-1486C | Recombinant Cynomolgus CD46 protein, His-tagged | +Inquiry |
CD46-2331G | Recombinant Guinea Pig CD46 Protein (36-316 aa), His-tagged | +Inquiry |
CD46-0822H | Recombinant Human CD46 Protein | +Inquiry |
CD46-162H | Recombinant Human CD46 Protein, His-tagged | +Inquiry |
CD46-568R | Recombinant Rhesus Macaque CD46 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD46-1964HCL | Recombinant Human CD46 cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (3)
Write a reviewThe CD46 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.
With the CD46 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.
Its unique properties make CD46 an invaluable tool for investigating cellular signaling pathways, protein-protein interactions, and membrane dynamics.
Q&As (5)
Ask a questionCD46 protein interacts with complement regulatory proteins and immune cells to regulate immune responses and maintain homeostasis.
Potential side effects of targeting CD46 protein for therapy may include disturbances in immune regulation and increased susceptibility to infections.
CD46 protein regulates the activation of complement system and modulates T cell responses, contributing to immune regulation.
Mutations in the CD46 gene have been associated with genetic disorders such as atypical hemolytic uremic syndrome (aHUS) and other complement-related disorders.
CD46 protein has been implicated in cancer progression and treatment resistance, particularly in certain types of leukemia and solid tumors.
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