Active Recombinant Human CD86, Fc-tagged, Biotinylated
Cat.No. : | CD86-584H |
Product Overview : | The recombinant human CD86-Fc fusion protein is expressed as a 452 amino acid protein consisting of Ala24 - Pro247 region of CD86 (UniProt accession #P42081) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Binds human CD28 and induces IL-2 secretion by Jurkat human acute T cell leukemia cells |
Molecular Mass : | Calculated molecular mass 51.1 kDa; estimated by SDS-PAGE under reducing condition ~80 kDa probably due to glycosylation |
AA Sequence : | APLKIQAYFNETADLPCQFANSQNQ SLSELVVFWQDQENLVLNEVYLGKE KFDSVHSKYMGRTSFDSDSWTLRL HNLQIKDKGLYQCIIHHKKPTGMIR IHQMNSELSVLANFSQPEIVPISNI TENVYINLTCSSIHGYPEPKKMSV LLRTKNSTIEYDGVMQKSQDNVTEL YDVSISLSVSFPDVTSNMTIFCILE TDKTRLLSSPFSIELEDPQPPPDH IPSTGTHTCPPCPAPELLGGPSVFL FPPKPKDTLMISRTPEVTCVVVDVS HEDPEVKFNWYVDGVEVHNAKTKP REEQYNSTYRVVSVLTVLHQDWLNG KEYKCKVSNKALPAPIEKTISKAKG QPREPQVYTLPPSREEMTKNQVSL TCLVKGFYPSDIAVEWESNGQPENN YKTTPPVLDSDGSFFLYSKLTVDKS RWQQGNVFSCSVMHEALHNHYTQK SLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | CD86 CD86 molecule [ Homo sapiens ] |
Official Symbol : | CD86 |
Synonyms : | CD86; CD86 molecule; CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7 2 antigen); T-lymphocyte activation antigen CD86; B lymphocyte antigen B7 2; B7 2; B7.2; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); B70; B7-2; LAB72; CD28LG2; MGC34413; |
Gene ID : | 942 |
mRNA Refseq : | NM_001206924 |
Protein Refseq : | NP_001193853 |
MIM : | 601020 |
UniProt ID : | P42081 |
Chromosome Location : | 3q21 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; |
Function : | coreceptor activity; protein binding; receptor activity; |
Products Types
◆ Lysates | ||
CD86-1971RCL | Recombinant Rat CD86 cell lysate | +Inquiry |
CD86-2619HCL | Recombinant Human CD86 cell lysate | +Inquiry |
CD86-1013CCL | Recombinant Cynomolgus CD86 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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