Active Recombinant Human DcR3, HIgG1 Fc-tagged
| Cat.No. : | DcR3-678H |
| Product Overview : | A soluble dimeric fusion protein consisting of the extracellular domain of human DcR3(O95407) (Val24-His300) was fused to human IgG1 Fc. |
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| Species : | Human |
| Source : | CHO |
| Tag : | Fc |
| Protein Length : | 24-300 a.a. |
| Description : | This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| AA Sequence : | A soluble dimeric fusion protein consisting of the extracellular domain of human DcR3(O95407) (Val24-His300) was fused to human IgG1 Fc. |
| Endotoxin : | <0.06eu mu;g="" as="" determined="" by="" lal=""> |
| Purity : | >98%(SDS-PAGE) |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Gene Name | TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens (human) ] |
| Official Symbol | DcR3 |
| Synonyms | TNFRSF6B; M68; TR6; DCR3; M68E; DJ583P15.1.1; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; decoy receptor 3; decoy receptor for Fas ligand |
| Gene ID | 8771 |
| mRNA Refseq | NM_003823 |
| Protein Refseq | NP_003814 |
| MIM | 603361 |
| UniProt ID | O95407 |
| Chromosome Location | 20q13.3 |
| Pathway | Apoptosis Modulation and Signaling; Cytokine-cytokine receptor interaction; Cytosolic Iron-sulfur Cluster Assembly |
| Function | protein binding; receptor activity |
| ◆ Recombinant Proteins | ||
| DcR3-678H | Active Recombinant Human DcR3, HIgG1 Fc-tagged | +Inquiry |
Not For Human Consumption!
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