Active Recombinant Human DLL4 protein, His-tagged
Cat.No. : | DLL4-2235H |
Product Overview : | Recombinant Human DLL4 protein(NP_061947.1)(Met1-Pro524), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its ability to bind human Notch1 in a functional ELISA.2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-10 µg/mL in the presence of 500 ng/mL recombinant human BMP2. |
Molecular Mass : | The recombinant human DLL4 consists of 509 amino acids and predicts a molecular mass of 55.7 kDa. As a result of glycosylation, the apparent molecular mass of rhDLL4 is approximately 55-70 kDa band in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Pro524 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 98 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Publication : |
The Special Role of JAK/STAT, and Notch Signaling Pathways in Cancer Pathogenesis (2023)
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Gene Name : | DLL4 delta-like 4 (Drosophila) [ Homo sapiens ] |
Official Symbol : | DLL4 |
Synonyms : | DLL4; delta-like 4 (Drosophila); delta like 4 homolog (Drosophila); delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4; hdelta2; MGC126344; |
Gene ID : | 54567 |
mRNA Refseq : | NM_019074 |
Protein Refseq : | NP_061947 |
MIM : | 605185 |
UniProt ID : | Q9NR61 |
Products Types
◆ Recombinant Protein | ||
Dll4-2402M | Recombinant Mouse Dll4 Protein, His (Fc)-Avi-tagged | +Inquiry |
DLL4-2687H | Recombinant Human DLL4 Protein, GST-tagged | +Inquiry |
DLL4-1349H | Recombinant Human DLL4 Protein, His&GST-tagged | +Inquiry |
DLL4-201H | Recombinant Human DLL4 Protein, His-tagged | +Inquiry |
DLL4-001H | Recombinant Human DLL4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
DLL4-2495MCL | Recombinant Mouse DLL4 cell lysate | +Inquiry |
DLL4-2507HCL | Recombinant Human DLL4 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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