Active Recombinant Human Fas (TNF receptor superfamily, member 6)
Cat.No. : | CSF3R-3815H |
Product Overview : | A DNA sequence encoding the extracellular domain (Met 1-Pro 621) of human CSF3R (NP_000751.1) precursor was expressed with the fused Fc region of human IgG1 at the C-terminus. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CSF3R-3815H |
Description : | CSF3R which belongs to the cytokine receptor superfamily, is a cell surface receptor for colony stimulating factor 3, a cytokine that plays a critical role in the regulation of the activation, proliferation, differentiation, and survival of the neutrophilic granulocyte lineage. |
Source : | Human |
Host : | Human Cells |
Form : | Lyophilized from sterile PBS, pH 7.4, Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Purity : | > 95 % as determined by SDS-PAGE |
Bio-activity : | Measured by its ability to inhibit the GCSF-induced proliferation of NFS-60 mouse myeloid cells. The ED50 for this effect is typically 1-4 ng/ml in the presence of 0.125 ng/mL of recombinant human GCSF. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C. |
Predicted N terminal : | Glu 25 |
Molecular Mass : | The mature recombinant human CSF3R is a disulfide-linked homodimeric protein. The reduced monomer consists of 835 amino acids and predicts a molecular mass of 93.3 KDa. By SDS-PAGE under reducing conditions, the apparent molecular mass of rh CSF3R monomer is approximately 120-130 KDa due to glycosylation. |
Storage : | Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | CSF3R colony stimulating factor 3 receptor (granulocyte) [ Homo sapiens ] |
Official Symbol : | CSF3R |
Synonyms : | CSF3R; colony stimulating factor 3 receptor (granulocyte); CD114; GCSFR; granulocyte colony-stimulating factor receptor; G-CSF-R; CD114 antigen; G-CSF receptor; OTTHUMP00000009703; OTTHUMP00000009704; OTTHUMP00000009705 |
Gene ID : | 1441 |
mRNA Refseq : | NM_000760 |
Protein Refseq : | NP_000751 |
MIM : | 138971 |
UniProt ID : | Q99062 |
Chromosome Location : | 1p35-p34 |
Pathway : | Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway; Pathways in cancer |
Function : | cytokine receptor activity; receptor activity |
Products Types
◆ Recombinant Protein | ||
CSF3R-1974H | Recombinant Human CSF3R Protein | +Inquiry |
CSF3R-259H | Recombinant Human CSF3R Protein, His-tagged | +Inquiry |
CSF3R-2164H | Recombinant Human CSF3R Protein, His-tagged | +Inquiry |
CSF3R-023H | Recombinant Human CSF3R Protein, C-His-tagged | +Inquiry |
CSF3R-1251H | Recombinant Human CSF3R Protein (25-620 aa), GST-tagged | +Inquiry |
◆ Lysates | ||
CSF3R-1803HCL | Recombinant Human CSF3R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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