Active Recombinant Human FCER1A protein, Fc-tagged
Cat.No. : | FCER1A-1460H |
Product Overview : | Recombinant Human FCER1A protein(Val26-Leu204), fused with Fc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant. |
Bio-activity : | Loaded Human Fc epsilon RI alpha, Fc Tag on AHC Biosensor, can bind Immunoglobulin E, Human Plasma with an affinity constant of 0.07 nM as determined in BLI assay (ForteBio Octet Red96e). |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminusThe protein has a calculated MW of 47.3 kDa. The protein migrates as 55-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Proteinlength : | Val26-Leu204 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Protein length : | Val26-Leu204 |
Gene Name : | FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide [ Homo sapiens ] |
Official Symbol : | FCER1A |
Synonyms : | FCER1A; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; FCE1A; high affinity immunoglobulin epsilon receptor subunit alpha; Fc-epsilon RI-alpha; Fc epsilon RI alpha-chain; igE Fc receptor subunit alpha; Fc IgE receptor, alpha polypeptide; high affinity immunoglobulin epsilon receptor alpha-subunit; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; FcERI; |
Gene ID : | 2205 |
mRNA Refseq : | NM_002001 |
Protein Refseq : | NP_001992 |
MIM : | 147140 |
UniProt ID : | P12319 |
Products Types
◆ Recombinant Protein | ||
FCER1A-245H | Recombinant Human FCER1A Protein, His-tagged | +Inquiry |
FCER1A-1961R | Recombinant Rat FCER1A Protein, His (Fc)-Avi-tagged | +Inquiry |
FCER1A-338H | Recombinant Human FCER1A Protein(Val26-Gln205), His-tagged | +Inquiry |
FCER1A-25H | Active Recombinant Human FCER1A Protein (26-205aa), C-His tagged | +Inquiry |
FCER1A-1209H | Recombinant Human FCER1A Protein, His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
FCER1A-1389MCL | Recombinant Mouse FCER1A cell lysate | +Inquiry |
FCER1A-1394HCL | Recombinant Human FCER1A cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewFCER1A can maintain its biological activity and structural integrity under specific experimental conditions.
FCER1A quality is stable and reliable, with no significant differences between batches.
FCER1A has high chemical and physical stability and is suitable for long-term storage and use.
Q&As (6)
Ask a questionModulation of FCER1A expression can be achieved through techniques such as gene knockout, gene silencing, or gene transduction. In addition, its expression levels can also be affected by altering environmental factors such as nutrition, inflammation, etc.
The expression level of FCER1A can be detected by gene expression profiling or immunohistochemistry.
FCER1A plays a key role in the immune system, recognizing and presenting antigens to T cell receptors, thereby initiating an adaptive immune response.
Studies have shown that FCER1A is associated with the risk of some autoimmune diseases, inflammatory diseases, and certain cancers.
Studying FCER1A can help to gain insight into the mechanisms of immune response and inflammatory response, which is of great significance for the development of new drugs and therapeutic strategies. In addition, it is also of great value for understanding the pathogenesis and prevention of diseases.
FCER1A has complex associations with other genes and proteins, such as its interaction with T cell receptors, inflammatory factors, etc.
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