Active Recombinant Human FGFR2 protein

• Cat.No.: FGFR2-2593H
• Product Overview: Active Recombinant Human FGFR-2/KGFR/CD332 Protein is produced by insect cell-baculovirus expression system. The target protein is expressed with sequence (Pro458-Gln778) of human FGFR-2 (Accession #NP_000132.3).

Specification

• Source: Baculovirus-Infected Sf9 Cells
• Species: Human
• Tag: N/A
• Form: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
• Bio-activity: 1.Measured by its ability to inhibit FGF-acidic dependent proliferation of Balb/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 0.21-0.84 ng/mL.
  2.Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human FGFR2 at 2 μg/mL (100 μL/well) can bind Recombinant Human FGF1 with a linear range of 0.128-48.3 ng/mL.
• Molecular Mass: 35 kDa
• Protein Length: Pro458-Gln778
• Endotoxin: < 1.0 EU/μg of the protein by LAL method.
• Purity: > 97% by SDS-PAGE.
• Storage: Store the lyophilized protein at -20°C to -80 °C for long term.
  After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
• Reconstitution: Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

Gene Information

• Gene Name: FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ]
• Official Symbol: FGFR2
• Synonyms: FGFR2; fibroblast growth factor receptor 2; bacteria expressed kinase , BEK, CFD1, craniofacial dysostosis 1 , Jackson Weiss syndrome , JWS, keratinocyte growth factor receptor , KGFR; CD332; CEK3; Crouzon syndrome; ECT1; K SAM; Pfeiffer syndrome; TK14; TK25; FGFR-2; FGF receptor; soluble FGFR4 variant 4; bacteria-expressed kinase; hydroxyaryl-protein kinase; keratinocyte growth factor receptor; BEK fibroblast growth factor receptor; protein tyrosine kinase, receptor like 14; BEK; JWS; CFD1; KGFR; BFR-1; K-SAM; FLJ98662
• Gene ID: 2263
• mRNA Refseq: NM_000141
• Protein Refseq: NP_000132
• MIM: 176943
• UniProt ID: P21802