ICOS-1533H
Optional Service: Optional requirements on this protein
Product Overview :
The extracellular domain of human CD278 [ICOS] (NP_036224.1) (Glu21-Leu139) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell.
Description :
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimersand plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
Source :
CHO cells
Species :
Human
Tag :
HIgG1 Fc-tagged
Form :
Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity :
Measured by its ability to inhibit human T cell proliferation induced by rhB7-H2/Fc Chimera in the presence of anti-CD3.
Molecular Mass :
40 KDa (monomer)
AA Sequence :
Glu21-Leu139
Endotoxin :
<0.06 eu/μg as determined by lal>
Purity :
>98%, by SDS-PAGE under reducing conditions.
Stability :
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.