Active Recombinant Human IFNG Protein (Gln24-Gln166), GMP Grade, Animal-Free
Cat.No. : | IFNG-30HG |
Product Overview : | GMP recombinant human IFN-gamma protein (Gln24-Gln166) with an N-terminal Met was expressed in E. coli, produced in an Animal-Free laboratory and manufactured and tested under cGMP guidelines. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. |
Source : | E. coli |
Species : | Human |
Bio-activity : | Measured in anti-viral assays using HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 0.15-0.75 ng/mL. The specific activity of recombinant human IFN-gamma is >2.0 x 107 IU/mg, which is calibrated against the human IFN-gamma Standard. |
Molecular Mass : | Predicted Molecular Mass: 16.9 kDa SDS-PAGE: 17 kDa, reducing conditions |
Protein Length : | Gln24-Gln166 |
N-terminal Sequence Analysis : | Met-Gln24-Asp-Pro-Tyr-Val-Lys-Glu-Ala-Glu |
Endotoxin : | <0.01 EU/ μg of the protein by the LAL method. |
Purity : | >97%, by SDS-PAGE with silver staining, under reducing conditions. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. A minimum of 12 months when stored at ≤ -20 centigrade as supplied. Refer to lot specific COA for the Use by Date. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, ≤ -20 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in Sodium Succinate, Mannitol and Tween® 80. |
Reconstitution : | Reconstitute at 200 μg/mL in sterile, deionized water. |
Shipping : | The product is shipped with polar packs. |
Gene Name : | IFNG interferon, gamma [ Homo sapiens ] |
Official Symbol : | IFNG |
Synonyms : | IFNG; interferon, gamma; interferon gamma; IFN-gamma; immune interferon; IFG; IFI; |
Gene ID : | 3458 |
mRNA Refseq : | NM_000619 |
Protein Refseq : | NP_000610 |
MIM : | 147570 |
UniProt ID : | P01579 |
Products Types
◆ Recombinant Protein | ||
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Ifng-009I | Active Recombinant Rat Ifng Protein (135 aa) | +Inquiry |
IFNG-8549H | Active Recombinant Human IFNG protein(Met1-Gln166) | +Inquiry |
IFNG-2028R | Recombinant Rhesus Macaque IFNG Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IFNG-1007FCL | Recombinant Ferret IFNG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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