Active Recombinant Human IL-23 Protein
Cat.No. : | IL23A-05H |
Product Overview : | Recombinant Human IL-23 p40 (Ile23-Ser328) and Human IL-23 p19 (Arg20-Pro189) without tag was expressed in Spodoptera frugiperda, Sf 21. |
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Source : | Sf 21 |
Species : | Human |
Bio-activity : | Measured by its ability to induce IL-17 secretion by mouse splenocytes. The ED50 for this effect is 0.05-0.3 ng/mL. |
Molecular Mass : | Predicted Molecular Mass: 55.0 kDa (IL-23 single chain); 36.5 kDa (p40) & 18.5 kDa (p19) SDS-PAGE: 65 kDa, 43-45 kDa and 20 kDa, reducing conditions |
N-terminal Sequence Analysis : | Ile23 (IL-23 single chain & p40) & Ala21 (p19) |
Endotoxin : | <1.0 EU/μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in MES, NaCl and EDTA with BSA as a carrier protein. |
Reconstitution : | Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | IL23A interleukin 23 subunit alpha [ Homo sapiens (human) ] |
Official Symbol : | IL23A |
Synonyms : | IL23A; interleukin 23 subunit alpha; P19; SGRF; IL-23; IL-23A; IL23P19; interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; IL-23p19; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin 23, alpha subunit p19; interleukin-23 subunit p19; interleukin-six, G-CSF related factor |
Gene ID : | 51561 |
mRNA Refseq : | NM_016584 |
Protein Refseq : | NP_057668 |
MIM : | 605580 |
UniProt ID : | Q9NPF7 |
Products Types
◆ Recombinant Protein | ||
IL23A-179H | Recombinant Active Human IL23A Protein, His-tagged(N-ter) | +Inquiry |
IL23A-2358H | Recombinant Human IL23A protein(Met1-Pro189), mFc-tagged | +Inquiry |
IL23A-32H | Active Recombinant Human IL23A Protein, Animal Free | +Inquiry |
Il23a-2304M | Recombinant Mouse Il23a Protein, His-tagged | +Inquiry |
Il23a-3515M | Active Recombinant Mouse Il23a Protein | +Inquiry |
◆ Lysates | ||
IL23A-5231HCL | Recombinant Human IL23A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewCoupled with the manufacturer's exceptional technical support and commitment to customer satisfaction, researchers can confidently utilize the IL23A protein in their studies, knowing that they have the necessary resources and assistance to succeed.
Its remarkable attributes and consistent results make it an indispensable tool in various experimental applications.
Highly recommended for its exceptional performance in ELISA, the IL23A protein is a top contender for researchers involved in protein electron microscopy structure analysis.
Q&As (6)
Ask a questionPlease inquiry our product manager with specific product.
Yes, drugs like ustekinumab and risankizumab, which target IL23A, have been approved for certain autoimmune diseases.
IL23A primarily plays a role in regulating the adaptive immune response.
IL23A is associated with the inflammation of the spine and joints seen in ankylosing spondylitis, making it a target for therapeutic intervention.
In rheumatoid arthritis, IL23A is involved in the dysregulation of the immune system, leading to joint inflammation and damage.
IL23A is implicated in the pathogenesis of Crohn's disease, contributing to chronic inflammation in the gastrointestinal tract.
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