Active Recombinant Human IL2 Protein

Species :	Human
Source :	CHO
Description :	Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Form :	Sterile Filtered White lyophilized (freeze-dried) powder.
Bio-activity :	ED50 < 2 ng/mL, measured in a cell proliferation assay using CTLL-2 cells.
Molecular Mass :	15~16 kDa, observed by reducing SDS-PAGE.
AA Sequence :	APTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
Endotoxin :	< 0.2 EU/μg, determined by LAL method.
Purity :	> 95% as analyzed by SDS-PAGE.
Storage :	Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade.
Storage Buffer :	Lyophilized after extensive dialysis against PBS..
Reconstitution :	Reconstituted in ddH2O or PBS at 100 μg/mL.

Gene Name	IL2 interleukin 2 [ Homo sapiens ]
Official Symbol	IL2
Synonyms	IL2; interleukin 2; interleukin-2; IL 2; T cell growth factor; TCGF; aldesleukin; involved in regulation of T-cell clonal expansion; IL-2; lymphokine;
Gene ID	3558
mRNA Refseq	NM_000586
Protein Refseq	NP_000577
MIM	147680
UniProt ID	P60568