Active Recombinant Human IL22, HIgG1 Fc-tagged, mutant

• Cat.No.: IL22-562H
• Product Overview: The extracellular domain of human IL-22 (NP_065386.1) (Ala34-ILe179) is fused to the N-terminus of the Fc region of a mutant human IgG1 was expressed in CHO cell.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Protein Length: 34-179 a.a.
• Description: L22 (interleukin 22) is a protein-coding gene. Diseases associated with IL22 include?chronic mucocutaneous candidiasis, and?candidiasis, and among its?related super-pathways?are?MIF Mediated Glucocorticoid Regulation?and?Regulation of eIF4 and p70S6K. GO annotations related to this gene include?cytokine activity?and?interleukin-22 receptor binding.
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: The Biological Activity was determined by the ability to activiate STAT following receptor ligand interaction.
• Molecular Mass: 46 KDa (monomer)
• AA Sequence: Ala34-ILe179
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: IL22 interleukin 22 [ Homo sapiens ]
• Official Symbol: IL22
• Synonyms: IL22; interleukin 22; interleukin-22; IL 10 related T cell derived inducible factor; IL 21; IL 22; IL D110; IL TIF; ILTIF; MGC79382; MGC79384; TIFa; TIFIL 23; zcyto18; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL-22; IL-TIF; IL-D110; TIFIL-23
• Gene ID: 50616
• mRNA Refseq: NM_020525
• Protein Refseq: NP_065386
• MIM: 605330
• UniProt ID: Q9GZX6
• Chromosome Location: 12q15
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem
• Function: cytokine activity; interleukin-22 receptor binding