Active Recombinant Human IL28A Protein (Pro27-Val200), C-His tagged, Animal-free, Carrier-free

Cat.No. : IL28A-129H
Product Overview : Recombinant Human IL28A Protein (Pro27-Val200) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.
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Description : Interleukin 28A (IL-28A) predicts a molecular mass of 22.3 kDa. IL-28 comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an antiviral state by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G.
Source : E. coli
Species : Human
Tag : C-His
Form : Lyophilized
Bio-activity : Measure by its ability to protect HepG2 cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is < 20 ng/mL.
Molecular Mass : The protein has a calculated MW of 20.60 kDa.
The protein migrates as 20 kDa under reducing condition (SDS-PAGE analysis).
Protein Length : Pro27-Val200
Endotoxin : < 0.1 EU/μg of the protein by the LAL method.
Purity : >98% as determined by SDS-PAGE analysis.
Storage : This product is stable after storage at:
-20 centigrade for 12 months in lyophilized state from date of receipt.
-20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
Avoid repeated freeze/thaw cycles.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0.
Reconstitution : It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Shipping : The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.
SDS-PAGE:
Gene Name : IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens (human) ]
Official Symbol : IL28A
Synonyms : IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon lambda-2; interferon-lambda 2; IL-28A;
Gene ID : 282616
mRNA Refseq : NM_172138
Protein Refseq : NP_742150
MIM : 607401
UniProt ID : Q8IZJ0

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the main mechanism of action of IL28A? 05/24/2021

It can enhance the body's immunity to pathogens by activating the immune system.

What is the role IL28A on the immune system? 03/11/2021

IL28A regulates the activity and differentiation of immune cells and enhances the function of the immune system.

What are the pharmacokinetic characteristics of IL28A? 03/09/2021

It has a long half-life and low clearance, which can maintain a stable plasma concentration.

How's the progress of clinical trials of IL28A? 06/20/2020

IL28A is undergoing several clinical trials and is currently showing some efficacy.

How the synthesis and purification method of IL28A? 06/19/2020

This protein is usually synthesized using recombinant DNA technology and purified by column chromatography and other methods.

What are the application prospects of IL28A in tumor therapy? 08/10/2019

IL28A can regulate immune response and enhance anti-tumor immunity in tumor therapy.

Customer Reviews (3)

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Reviews
11/15/2022

    No need to prepare a special environment, storage conditions are very simple, can be stored for a long time.

    10/04/2020

      Very stable, strong anti-pollution ability, the experimental results are very good.

      07/16/2019

        The labeling effect is very good, and fluorescent labeling can be carried out.

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