Active Recombinant Human IL3RA protein, His-tagged
| Cat.No. : | IL3RA-2652H |
| Product Overview : | Recombinant Human IL-3RA/CD123 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Lys20-Arg305) of human IL3RA/CD123 (Accession #NP_002174.1) fused with a 6×His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
| Source : | HEK293 |
| Species : | Human |
| Tag : | His |
| Form : | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized recombinant Human IL3 at 4 μg/mL (100 μL/well) can bind recombinant Human IL3RA, the EC50 of Human IL3RA is 5.3 μg/mL. |
| Molecular Mass : | 145-150kDa |
| Protein Length : | Lys20-Arg305 |
| Endotoxin : | < 0.1 EU/μg of the protein by LAL method. |
| Purity : | > 90% by SDS-PAGE. |
| Storage : | Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week. |
| Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. |
| Gene Name : | IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ] |
| Official Symbol : | IL3RA |
| Synonyms : | IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174; |
| Gene ID : | 3563 |
| mRNA Refseq : | NM_002183 |
| Protein Refseq : | NP_002174 |
| MIM : | 308385 |
| UniProt ID : | P26951 |
Products Types
| ◆ Recombinant Protein | ||
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| IL3RA-1120H | Recombinant Human IL3RA Protein (Met1-Arg305), HlgG1 Fc-tagged | +Inquiry |
| IL3RA-1176H | Recombinant Human IL3RA Protein, His (Fc)-Avi-tagged | +Inquiry |
| IL3RA-5184H | Active Recombinant Human IL3RA Protein, His/Flag/StrepII-tagged | +Inquiry |
| IL3RA-4517M | Recombinant Mouse IL3RA Protein, His (Fc)-Avi-tagged | +Inquiry |
| ◆ Lysates | ||
| IL3RA-2433HCL | Recombinant Human IL3RA cell lysate | +Inquiry |
| IL3RA-742CCL | Recombinant Canine IL3RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.
Customer Reviews (3)
Write a reviewIt is highly specific, that is, it binds only to its receptor IL-3R, and it has high potential in fighting disease and drug discovery -
Depending on the need, different IL-3Rα variants or mutants can be customized through techniques such as genetic modification to achieve the production of their specific properties. -
IL-3rα, by binding to its receptor, plays an important role in regulating biological processes such as cell proliferation and differentiation, and its biological activity needs to be guaranteed and can be detected by biological identification and other methods. -
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