Active Recombinant Human ITGAV & ITGB5 Heterodimer Protein, His-tagged
Cat.No. : | ITGAV&ITGB5-364H |
Product Overview : | Recombinant Human ITGAV & ITGB5 Heterodimer Protein, His-tagged is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) & Gly 24 - Asn 719 (ITGB5) (Accession # NP_002201 (ITGAV) & AAH06541 (ITGB5)). Predicted N-terminus: Phe 31 (ITGAV) & Gly 24 (ITGB5). Human ITGAV & ITGB5 Heterodimer Protein, produced by co-expression of ITGAV and ITGB5, has a calculated MW of 113 kDa (ITGAV) and 81.9 kDa (ITGB5). Subunit ITGAV is fused with polyhistidine tag at the C-terminus and followed by a acidic tail and subunit ITGB5 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 145 kDa (ITGAV) and 100-116 kDa (ITGB5) respectively due to glycosylation. |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Vitronectin at 2 μg/mL (100 μL/well) can bind Recombinant Human ITGAV & ITGB5 Heterodimer Protein, His-tagged with a linear range of 2-20 ng/mL (QC tested). |
Molecular Mass : | 113 kDa (ITGAV) & 81.9 kDa (ITGB5) |
Protein length : | Phe 31 - Val 992 (ITGAV) & Gly 24 - Asn 719 (ITGB5) |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Notes : | Please avoid repeated freeze-thaw cycles. |
Stability : | No activity loss is observed after storage at: 4-8 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
Gene Name : | ITGAV integrin, alpha V [ Homo sapiens ] & ITGB5 integrin, beta 5 [ Homo sapiens ] |
Official Symbol : | ITGAV & ITGB5 |
Synonyms : | ITGAV; integrin, alpha V; CD51; MSK8; VNRA; VTNR; DKFZp686A08142; & ITGB5; integrin, beta 5; integrin beta-5; FLJ26658; |
Gene ID : | 3685 & 3693 |
mRNA Refseq : | NM_001144999 & NM_002213 |
Protein Refseq : | NP_001138471 & NP_002204 |
MIM : | 193210 & 147561 |
UniProt ID : | P06756 & P18084 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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