Active Recombinant Human JAK2 Protein, V617F, Flag tagged

• Cat.No.: JAK2-02H
• Product Overview: Recombinant JAK2 (532-1132, V617F) protein that includes amino acids 532-1132 of human JAK2 protein (accession number NP_004963.1) was expressed in a baculovirus expression system with a point mutation Val617Phe, and contains an N-terminal FLAG tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Flag
• Protein Length: 532-1132 aa
• Form: Recombinant JAK2 (532-1132, V617F) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10% glycerol, 0.04% Triton X-100 and 0.5 mM TCEP.
• Molecular Mass: 71.1 kDa
• Purity: >88%
• Applications: Recombinant JAK2 (532-1132, V617F) protein is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• Concentration: 0.25 μg/μL

Gene Information

• Gene Name: JAK2 Janus kinase 2 [ Homo sapiens ]
• Official Symbol: JAK2
• Synonyms: JAK2; Janus kinase 2; tyrosine-protein kinase JAK2; JTK10; JAK-2; Janus kinase 2 (a protein tyrosine kinase); THCYT3
• Gene ID: 3717
• mRNA Refseq: NM_004972
• Protein Refseq: NP_004963
• MIM: 147796
• UniProt ID: O60674